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Table 2 Differentially expressed immune- and cell death-associated proteins in caecum-derived extracellular vesicles

From: Quantitative proteomic analysis of local and systemic extracellular vesicles during Eimeria falciformis infectious cycle in the host

Protein ID

Gene name

Protein description

Coverage (%)

Unique peptides (n)

Sequence alignment score

FC

cEVs, 0/68 hpi

cEVs, 0/116 hpi

cEVs, 0/7 dpi

cEVs, 0/10 dpi

P12815

Pdcd6

Programmed cell death protein 6

24

4

32.02

1.32

1.42

3.07

2.29

Q9JJF9

Sppl2a

Signal peptide peptidase-like 2A

5

4

34.43

1.57

0.79

2.16

3.13

P14437

H2-Aa

H-2 class II histocompatibility antigen

22

1

44.04

2.24

1.62

1.63

1.62

P01901

H2-K1

H-2 class I histocompatibility antigen

14

1

58.31

1.42

1.76

2.33

3.65

P29477

Nos2

Nitric oxide synthase, inducible

4

4

20.91

1.24

ND

1.32

1.29

Q9QZ85

Iigp1

Interferon-inducible GTPase 1

6

2

11.66

2.03

2.32

1.98

1.98

Q91WS2

Nlrp6

NACHT,LRR and PYD domains-containing protein 6

3

2

5.21

1.12

0.77

1.66

2.67

P05533

Ly6a

Lymphocyte antigen 6A-2/6E-1

16

1

35.53

1.52

1.21

1.36

0.69

O08692

Ngp

Neutrophilic granule protein

12

2

16.55

1.36

ND

7.79

2.76

P42225

Stat1

Signal transducer and Activator of transcription

11

6

5.58

1.48

2.43

2.2

ND

Q61735

Cd47

Leukocyte surface antigen CD47

16

4

26.63

ND

0.77

1.23

1.68

P70677

Casp3

Caspase-3

14

4

25.62

ND

1.58

1.21

0.76

Q08509

Eps8

Epidermal growth factor Receptor kinase substrate 8

11

9

57.71

0.63

0.69

1.94

2.67

O88456

Capns1

Calpain small subunit

3

1

5.77

1.26

1.62

1.68

1.48

Q99JW5

Epcam

Epithelial cell adhesion molecule

21

5

89.87

0.63

1.22

0.46

0.49

P01878

 

Ig alpha chain C region

11

3

39.71

0.57

0.45

0.29

0.19

Q2KHK6

Gsdmc2

Gasdermin-C2

6

3

15.83

0.7

0.58

0.29

0.32

P82198

Tgfbi

Transforming growth factor-beta-induced protein ig-h3

1

1

2.8

0.83

0.62

ND

0.37

P18531

Ighv3-6

Ig heavy chain V region 3-6

17

1

2.8

0.62

0.69

0.51

0.3

P11438

Lamp1

Lysosome-associated

membrane glycoprotein 1

6

2

21.15

0.83

0.7

0.64

0.83

P58682

Tlr8

Toll-like receptor 8

1

1

2.92

ND

0.57

0.15

0.17

Q3T9E4

Tgtp2

T-cell-specific guanine nucleotide triphosphate-binding protein

1

1

4.64

ND

0.62

0.32

0,61

P01831

Thy1

Thy-1 membrane glycoprotein

9

1

3.13

ND

0.75

0.54

0.6

  1. cEVs Caecum-derived extracellular vesicles, dpi days post-infection, FC fold change, hpi hours post-infection
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