Quantitative proteomic analysis of local and systemic extracellular vesicles during Eimeria falciformis infectious cycle in the host

Table 3 Differentially expressed immune-related proteins in serum- and caecum-derived extracellular vesicles

Protein ID	Gene name	Protein description	Coverage (%)	Unique peptides (n)	Sequence alignment score	FC
Protein ID	Gene name	Protein description	Coverage (%)	Unique peptides (n)	Sequence alignment score	sEVs/cEVs, 0 hpi	sEVs/cEVs, 68 hpi	sEVs/cEVs, 116 hpi	sEVs/cEvs, 7 dpi	sEVs/cEVs, 10 dpi
P01902	H2-K1	H-2 class I histocompatibility antigen	14	1	58.31	2.18	1.66	1.23	1.58	0.27
P82198	Tgfbi	Transforming growth factor-beta-induced protein ig-h3	88.8	128.5	2.8	0.75		1.56	0.71	1.45
Q9WU78	Pdcd6ip	Programmed cell death 6-interacting protein	173.9	50.4	143.72	2.77	1.5	1.44	0.51	0.61
P01027	c3	Complement C3	68.9	35	35.25	2.23	3.44	2.58	0.38
P63001	Rac1	Ras-related C3 botulinum toxin substrate 1	184.9	34.8	12.75	4	1.78	1.36	0.8	2.58
P13597	Icam1	Intercellular adhesion molecule 1	102.4	79.6	11.99		1.21		1.44	0.42
P01029	C4b	Complement C4-B	97	62.4	28.46		1.57	1.95	0.65	0.64
P01631		Ig kappa chain V-II region 26-10	85.2	43.2	23.02	2.35	2.01	1.29	0.45	0.75
Q9QWK4	Cd5l	CD5 antigen-like	83.4	49.2	5.27	1.47	1.6	1.9	0.68	0.77
P11672	Lcn2	Neutrophil gelatinase-associated lipocalin	50.1	14.2	6.02	1.97	3.47	4.22		0.46

cEVs Caecum-derived extracellular vesicles, dpi days post-infection, FC fold change, hpi hours post-infection, sEVs serum-derived extracellular vesicles

ISSN: 1756-3305