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Fig. 4 | Parasites & Vectors

Fig. 4

From: Excretory/secretory products from Trichinella spiralis adult worms ameliorate myocardial infarction by inducing M2 macrophage polarization in a mouse model

Fig. 4

Ts-AES inhibited excessive myocardial fibrosis and promoted ventricular remodeling after MI in mice. a Representative sections of Masson staining of infarcted heart tissue in each group after MI (400 × , Scale bar: 50 μm). b Thickness of the left ventricular wall in each group (n = 4). c Percentage infarction area of LV in each group (n = 4). d Fibrosis area of the infarction zone (IZ) in each group (n = 4). e mRNA transcriptional levels of α-SMA in the infarction zone (n = 6). f mRNA transcriptional levels of VEGF in infarct region of heart in each treated group (n = 6). The results are presented as mean ± SEM, *P < 0.05, **P < 0.01, ***P < 0.001

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