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Fig. 3 | Parasites & Vectors

Fig. 3

From: Echinococcus granulosus cyst fluid inhibits inflammatory responses through inducing histone demethylase KDM5B in macrophages

Fig. 3

EgCF reduced H3K4me3 modification. THP-1 and RAW 264.7 cells were treated with EgCF (50% v/v) and LPS (1 μg/ml) for 6 h. Levels of H3K4me3, H3K9me3, and H3K36me3 were measured by Western blotting (A, B). Enrichment of H3K4me3 at IL-6 and TNF-α promoters in mouse bone marrow-derived macrophages (GSM2419196, GSM2419204, GSM2419211) (C, D) and human THP-1 cells (GSM2108047) (E, F)

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