Fig. 6

Transcriptome sequencing of spleen tissues to find differentially expressed genes at the 8th week post-infection. NL: normal group; NI: normal + infection group; OB: obesity + infection group; UN: undernutrition 75% + infection group. A FPKM density distribution and violin plots for all samples. In violin plots, the horizontal line in the middle of the box is the median, the upper and lower edges of the box are at 75%; the upper and lower limits are at 90%. B Clustering of DEGs in all samples. Each column is a sample, and the horizontal axis represents different genes, with red representing high expression genes and green representing low expression genes. C Venn diagram of DEGs in each group. D The number of DEGs in the pairwise comparison of each group. Red represents upregulated genes, and green represents downregulated genes. E MA plots of DEGs between groups. Red dots represent upregulated genes, blue dots represent downregulated genes, and gray dots represent non-differentially expressed genes compared with the control group