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Fig. 7 | Parasites & Vectors

Fig. 7

From: Upregulation of PD-1/PD-L1 and downregulation of immune signaling pathways lead to more severe visceral leishmaniasis in undernutrition mice

Fig. 7

KEGG and GSEA enrichment analysis of differentially expressed genes. NL: normal group; NI: normal + infection group; OB: obesity + infection group; UN: undernutrition 75% + infection group. A The top 10 KEGG pathways with the most significant enrichment. The degree of enrichment was measured by the rich factor, FDR (false discovery rate) value and the number of genes enriched in the pathway. The greater the rich factor was, the greater the degree of enrichment. FDR generally ranges from 0 to 1, and the closer it is to zero, the more significant the enrichment is. The larger the bubble diameter in the figure, the more differentially expressed genes enriched in the pathway. B GSEA analysis results of important signaling pathways

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Parasites & Vectors

ISSN: 1756-3305

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