Fig. 8From: Upregulation of PD-1/PD-L1 and downregulation of immune signaling pathways lead to more severe visceral leishmaniasis in undernutrition micePPI analysis of differentially expressed genes and screening of hub genes. NL: normal group; NI: normal + infection group; OB: obesity + infection group; UN: undernutrition 75% + infection group. Each ellipse in the figure represents a protein. Red represents upregulated expression, and green represents downregulated expression compared with the control group. A PPI interaction circular map of DEGs. B Hub gene clusters of DEGs between normal + infection and undernutrition 75% + infection groups. C Hub gene clusters of DEGs between normal + infection and obesity + infection groups. D Hub gene clusters of DEGs between normal and normal + infection groupBack to article page