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Fig. 8 | Parasites & Vectors

Fig. 8

From: Upregulation of PD-1/PD-L1 and downregulation of immune signaling pathways lead to more severe visceral leishmaniasis in undernutrition mice

Fig. 8

PPI analysis of differentially expressed genes and screening of hub genes. NL: normal group; NI: normal + infection group; OB: obesity + infection group; UN: undernutrition 75% + infection group. Each ellipse in the figure represents a protein. Red represents upregulated expression, and green represents downregulated expression compared with the control group. A PPI interaction circular map of DEGs. B Hub gene clusters of DEGs between normal + infection and undernutrition 75% + infection groups. C Hub gene clusters of DEGs between normal + infection and obesity + infection groups. D Hub gene clusters of DEGs between normal and normal + infection group

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