Fig. 1

Lentinan ameliorated cognitive deficits in chronic Toxoplasma gondii-infected mice. The nest building test was used to estimate the ability of daily living of mice (a–c). a The nest score. b Untore nestler weight (amount of untore nesting material). c Representative nest of Con, ConL, Tg and TgL mice. The object location test was performed to evaluate the function of spatial memory of the mice (d–f). d Percentage of exploration time spent with the object in the novel place to total object exploration time. e The total object exploration time spent with the object in the familiar and novel place. f Representative track plots of Con, ConL, Tg and TgL mice recorded by SMART video tracking system in the testing phase. The novel object recognition test was performed to evaluate the object recognition memory of the mice (g–i). g Percentage of exploration time spent with the novel object to total object exploration time. h The total object exploration time. i Representative track plots of Con, ConL, Tg and TgL mice. Con: control group (n = 10); ConL: Con + Lentinan group (n = 10); Tg: chronic T. gondii-infected group (n = 10); TgL: Tg + Lentinan group (n = 10). Values are mean ± SEM. **P < 0.01, ***P < 0.001