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Fig. 5 | Parasites & Vectors

Fig. 5

From: Lentinan has a beneficial effect on cognitive deficits induced by chronic Toxoplasma gondii infection in mice

Fig. 5

Lentinan inhibited the pro-inflammatory cytokines and C1q production initiated by Toxoplasma gondii infection in the hippocampus. a Double immunofluorescence staining for Iba1 (red) and IL-6 (green) in the CA1 region of the hippocampus of Con, ConL, Tg and TgL mice (Scale bar: 50 μm). b Quantification of the mean fluorescence intensity of IL-6+ cells in the CA1 region of the hippocampus (n = 3, 3 images per mouse). c Percentage of Iba1+IL-6+ cells in Iba1+ cells (n = 3, 3 images per mouse). d–g mRNA expression of IL-1β, TNF-α, C1q, and IL-6, (n = 6–8). Con: control group; ConL: Con + Lentinan group; Tg: chronic T. gondii-infected group; TgL: Tg + Lentinan group. Values are mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001

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Parasites & Vectors

ISSN: 1756-3305

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