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Fig. 5 | Parasites & Vectors

Fig. 5

From: Echinococcus granulosus cyst fluid inhibits KDM6B-mediated demethylation of trimethylated histone H3 lysine 27 and interleukin-1β production in macrophages

Fig. 5

AD EgCF promotes the global level of trimethylated histone H3 lysine 27 (H3K27me3). PM and THP-1 cells were primed with LPS in the presence or absence of EgCF and then exposed to nigericin or ATP. Cell lysates were immunoblotted for H3K9me3, H3K27me3, and H3K36me3. Data are presented as mean + SEM of three independent experiments and compared using one-way ANOVA and Tukey’s test; *** P < 0.001. For other abbreviations, see Figs. 1 and  3

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