Table 3 Therapeutic responses and recurrence free condition in the patients*
Responses | ANPQ3 group (N = 172) | CQPQ14 group (N = 116) | Difference of percentage point (95% CI) | P value |
|---|---|---|---|---|
Mean fever clearance ± SD (range)—h | 27.1 ± 8.0 (24.0–48.0) | 35.0 ± 12.4 (24.0–72.0) | – |  < 0.0001 |
Fever clearance in 24 h—no. (%; 95% CI) | 150 (87.2; 81.3–91.8) | 64 (55.2; 45.7–64.4) | 32.0 (21.7–42.4) |  < 0.0001 |
Mean parasite clearance ± SD (range)—h | 27.9 ± 9.6 (24.0–72.0) | 36.8 ± 15.3 (24.0–96.0) | – | 0.0010 |
Parasite clearance in 24 h—no. (%; 95% CI) | 146 (84.9, 78.6–89.9) | 62 (53.5; 44.0–62.8) | 31.4 (20.9–42.0) |  < 0.0001 |
Recurrence free by day 28—no. (%; 95% CI) | 172 (100, 97.9–100) | 116 (100, 96.9–100) | 0 | 1.000 |
Recurrence free by day 42—no. (%; 95% CI) | 172 (100, 97.9–100) | 116 (100, 96.9–100) | 0 | 1.000 |
Recurrence free by day 56—no. (%; 95% CI) | 172 (100, 97.9–100) | 116 (100, 96.9–100) | 0 | 1.000 |
Recurrence free by day 70—no. (%; 95% CI) | 166 (96.5, 92.6–98.7) | 115 (99.1, 95.3–100.0) | −2.6 (−5.8 to 0.6) | 0.2481 |
Recurrence free by day 98—no. (%; 95% CI) | 163 (94.8, 90.3–97.6) | 114 (98.3, 93.9–99.8) | −3.5 (−7.6 to 0.6) | 0.2091 |
Recurrence free by day 182—no. (%; 95% CI) | 160 (93.0, 88.1–96.3) | 112 (96.6, 91.4–99.1) | −3.5 (−8.6 to 1.5) | 0.2946 |
Recurrence free by day 365—no. (%; 95% CI) | 152 (88.4, 82.6–92.8) | 108 (93.1, 86.9–97.0) | −4.7 (−11.4 to 1.9) | 0.2257 |