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Table 6 Number (%) of participants by mfAC category at Month 6, 12 and 18 by post-treatment SmfD and treatment

From: Onchocerca volvulus microfilariae in the anterior chambers of the eye and ocular adverse events after a single dose of 8 mg moxidectin or 150 µg/kg ivermectin: results of a randomized double-blind Phase 3 trial in the Democratic Republic of the Congo, Ghana and Liberia

SmfD

Moxidectin

Ivermectin

Any

0

1–5

6–10

11–20

21–40

 > 40

Any

0

1–5

6–10

11–20

21–40

 > 40

N (%)1

n

%2

n

%

n

%

n

%

n

%

n

%

N (%)1

n

%2

n

%

n

%

n

%

n

%

n

%

Month 6

Month 6

                         

0

875 (91.5)

830

94.9

37

4.2

4

0.5

4

0.5

    

54 (11.1)

54

100

          

 > 0–5

81 (8.5)

76

93.8

4

4.9

1

1.2

      

339 (69.6)

325

95.9

13

3.8

  

1

0.3

    

 > 5

0 (0)

            

94 (19.3)4

86

91.5

7

7.4

      

1

1.1

All

956 (100)

906

94.8

41

4.3

5

0.5

4

0.4

    

487 (100)

465

95.5

20

4.1

  

1

0.2

  

1

0.2

Month 12

Month 12

                         

0

436 (46.3)

434

99.5

2

0.5

        

24 (5.0)

24

100

          

 > 0–5

431 (45.8)

422

97.9

6

1.4

2

0.5

  

1

0.2

  

212 (44.5)

208

98.1

2

0.9

1

0.5

1

0.5

    

 > 5

74 (7.9)3

67

90.5

6

8.1

  

1

1.4

    

240 (50.4)4

223

92.9

15

6.3

1

0.4

    

1

0.4

All

941 (100)

923

98.1

14

1.5

2

0.2

1

0.1

1

0.1

  

476 (100)

455

95.6

17

3.6

2

0.4

1

0.2

  

1

0.2

Month 18

Month 18

                         

0

212 (28.0)

211

99.5

1

0.5

        

15 (3.9)

15

100

          

 > 0–5

376 (49.6)

374

99.5

1

0.3

1

0.3

      

130 (34.0)

128

98.5

2

1.5

        

 > 5

170 (22.4)3

163

95.9

7

4.1

        

237 (62.0)4

223

94.1

10

4.2

2

0.8

1

0.4

  

1

0.4

All

758 (100)

748

98.7

9

1.2

1

0.1

      

382 (100)

366

95.8

12

3.1

2

0.5

1

0.3

  

1

0.3

  1. 1% calculated across SmfD categories, 2% calculated by SmfD category. 3 maximum SmfD of 27.9 and 70.5 at Month 12, respectively, 4maximum SmfD 43.1, 76.5 and 101.3 at Month 6, 12 and 18, respectively (for further details see Additional file 1: Fig S3 and Fig S4)