Day of study | Date that chemical treatment was performed in the respective group | Experimental groups | Value Test2 | Pr > KW3 | |||||
---|---|---|---|---|---|---|---|---|---|
T01: fluralaner (2.5Â mg/kg) every 42Â days | T02: Fluralaner (2.5Â mg/kg) visual inspection for retreatment | T03: control (treatment when necessary) | |||||||
Mean 1 count ± standard deviation/median/range | Mean 1 count ± standard deviation/median/range | Mean 1 count ± standard deviation/median/range | |||||||
0* | T01 and T02 | 21.6 ± 3.4 | 21.0 (17–30) A | 21.6 ± 3.3 | 20.7 (18–30) A | 21.6 ± 3.1 | 21.7 (17–29.7) A | 0.15 | 0.9287 |
7 | T03 | 1.0 ± 1.1 | 1.0 (0–3) B | 1.3 ± 1.5 | 0.0 (0–4) B | 38.6 ± 9.0 | 36.0 (26–32) A | 30.42 |  < 0.0001 |
14 |  | 0.0 ± 0.0 | 0.0 (0–0) B | 0.0 ± 0.0 | 0.0 (0–0) B | 3.3 ± 3.4 | 2.0 (0–10) A | 27.78 |  < 0.0001 |
21 |  | 0.0 ± 0.0 | 0.0 (0–0) B | 0.0 ± 0.0 | 0.0 (0–0) B | 1.9 ± 1.9 | 3.0 (0–5) A | 18.83 | 0.0001 |
28 |  | 0.0 ± 0.0 | 0.0 (0–0) B | 0.0 ± 0.0 | 0.0 (0–0) B | 2.9 ± 2.7 | 4.0 (0–7) A | 21.68 |  < 0.0001 |
35 |  | 0.0 ± 0.0 | 0.0 (0–0) B | 0.0 ± 0.0 | 0.0 (0–0) B | 15.0 ± 7.5 | 14.0 (6–34) A | 41.71 |  < 0.0001 |
42 | T01 and T03 | 0.0 ± 0.0 | 0.0 (0–0) B | 0.1 ± 0.5 | 0.0 (0–2) B | 31.1 ± 10.6 | 31.0 (14–56) A | 40.13 |  < 0.0001 |
49 |  | 0.0 ± 0.0 | 0.0 (0–0) B | 2.3 ± 3.5 | 0.0 (0–11) A | 3.0 ± 3.0 | 3.0 (0–8) A | 13.59 | 0.0011 |
56 | T02 | 0.0 ± 0.0 | 0.0 (0–0) B | 4.7 ± 4.1 | 4.0 (0–14) A | 1.5 ± 1.8 | 1.0 (0–6) AB | 19.23 | 0.0001 |
63 |  | 0.0 ± 0.0 | 0.0 (0–0) A | 0.0 ± 0.0 | 0.0 (0–0) A | 0.5 ± 1.2 | 0.0 (0–4) A | 4.09 | 0.1293 |
70 |  | 0.0 ± 0.0 | 0.0 (0–0) B | 0.0 ± 0.0 | 0.0 (0–0) B | 5.6 ± 4.3 | 6.0 (0–13) A | 31.03 |  < 0.0001 |
77 |  | 0.0 ± 0.0 | 0.0 (0–0) B | 0.0 ± 0.0 | 0.0 (0–0) B | 9.3 ± 4.8 | 9.0 (3–18) A | 41.78 |  < 0.0001 |
84 | T01 and T03 | 0.0 ± 0.0 | 0.0 (0–0) B | 0.0 ± 0.0 | 0.0 (0–0) B | 31.3 ± 15.5 | 33.0 (10–64) A | 41.70 |  < 0.0001 |
91 |  | 0.0 ± 0.0 | 0.0 (0–0) B | 0.0 ± 0.0 | 0.0 (0–0) B | 1.5 ± 1.8 | 1.0 (0–6) A | 21.67 |  < 0.0001 |
98 |  | 0.0 ± 0.0 | 0.0 (0–0) B | 1.2 ± 2.6 | 0.0 (0–8) B | 4.3 ± 3.4 | 4.0 (0–10) A | 20.94 |  < 0.0001 |
105 |  | 0.0 ± 0.0 | 0.0 (0—0) B | 2.4 ± 4.0 | 0.0 (0–13) B | 6.8 ± 4.4 | 6.0 (0–13) A | 22.33 |  < 0.0001 |
112 | T02 and T03 | 0.0 ± 0.0 | 0.0 (0–0) B | 4.9 ± 6.0 | 2.0 (0–18) B | 61.9 ± 37.0 | 46.0 (9–125) A | 35.66 |  < 0.0001 |
119 |  | 0.0 ± 0.0 | 0.0 (0–0) B | 0.2 ± 0.6 | 0.0 (0–2) B | 3.8 ± 3.3 | 4.0 (0–9) A | 20.40 |  < 0.0001 |
126 | T01 | 0.0 ± 0.0 | 0.0 (0–0) B | 0.0 ± 0.0 | 0.0 (0–0) B | 4.3 ± 3.1 | 4.0 (0–10) A | 34.44 |  < 0.0001 |
133 |  | 0.0 ± 0.0 | 0.0 (0–0) B | 0.0 ± 0.0 | 0.0 (0–0) B | 1.1 ± 1.2 | 1.0 (0–4) A | 21.71 |  < 0.0001 |
140 | T03 | 0.0 ± 0.0 | 0.0 (0–0) B | 0.0 ± 0.0 | 0.0 (0–0) B | 41.1 ± 36.7 | 35.0 (4–156) A | 41.70 |  < 0.0001 |
147 |  | 0.0 ± 0.0 | 0.0 (0–0) A | 0.0 ± 0.0 | 0.0 (0–0) A | 0.9 ± 1.9 | 0.0 (0–6) A | 6.28 | 0.0734 |
154 |  | 0.0 ± 0.0 | 0.0 (0–0) A | 0.1 ± 0.3 | 0.0 (0–1) A | 1.5 ± 2.1 | 0.0 (0–6) A | 13.23 | 0.0613 |
161 |  | 0.0 ± 0.0 | 0.0 (0–0) B | 0.3 ± 0.7 | 0.0 (0–1) B | 1.3 ± 1.0 | 1.0 (0–3) A | 19.09 | 0.0001 |
168 | T01, T02 and T03 | 0.0 ± 0.0 | 0.0 (0–0) B | 3.6 ± 7.4 | 0.0 (0–21) B | 89.7 ± 61.7 | 68.0 (19–241) A | 36.18 |  < 0.0001 |
175 |  | 0.0 ± 0.0 | 0.0 (0–0) A | 0.0 ± 0.0 | 0.0 (0–0) A | 0.7 ± 1.0 | 0.0 (0–3) A | 13.46 | 0.0012 |
182 |  | 0.0 ± 0.0 | 0.0 (0–0) B | 0.0 ± 0.0 | 0.0 (0–0) B | 0.9 ± 0.8 | 1.0 (0–2) A | 21.73 |  < 0.0001 |
189 |  | 0.0 ± 0.0 | 0.0 (0–0) B | 0.0 ± 0.0 | 0.0 (0–0) B | 2.3 ± 2.5 | 2.0 (0–10) A | 10.31 |  < 0.0001 |
196 | T03 | 0.0 ± 0.0 | 0.0 (0–0) B | 0.0 ± 0.0 | 0.0 (0–0) B | 92.8 ± 65.0 | 85.0 (24–265) A | 41.69 |  < 0.0001 |
203 |  | 0.0 ± 0.0 | 0.0 (0–0) B | 0.0 ± 0.0 | 0.0 (0–0) B | 1.6 ± 2.1 | 1.0 (0–8) A | 21.71 |  < 0.0001 |
210 | T01 | 0.0 ± 0.0 | 0.0 (0–0) A | 0.0 ± 0.0 | 0.0 (0–0) A | 0.7 ± 1.0 | 0.0 (0–3) A | 13.46 | 0.0654 |
217 |  | 0.0 ± 0.0 | 0.0 (0–0) A | 0.0 ± 0.0 | 0.0 (0–0) A | 1.3 ± 3.1 | 0.0 (0–12) A | 13.46 | 0.0743 |
224 |  | 0.0 ± 0.0 | 0.0 (0–0) B | 0.0 ± 0.0 | 0.0 (0–0) B | 5.1 ± 3.7 | 5.0 (0–12) A | 04.38 |  < 0.0001 |
231 | T03 | 0.0 ± 0.0 | 0.0 (0–0) B | 0.0 ± 0.0 | 0.0 (0–0) B | 34.6 ± 24.4 | 29.0 (5–74) A | 41.71 |  < 0.0001 |
238 |  | 0.0 ± 0.0 | 0.0 (0–0) A | 0.0 ± 0.0 | 0.0 (0–0) A | 0.9 ± 1.1 | 0.0 (0–3) A | 16.09 | 0.0571 |
245 |  | 0.0 ± 0.0 | 0.0 (0–0) B | 0.0 ± 0.0 | 0.0 (0–0) B | 1.7 ± 1.5 | 2.0 (0–5) A | 27.79 |  < 0.0001 |
252 |  | 0.0 ± 0.0 | 0.0 (0–0) A | 0.0 ± 0.0 | 0.0 (0–0) A | 0.4 ± 0.8 | 0.0 (0–3) A | 8.57 | 0.0838 |
259 |  | 0.0 ± 0.0 | 0.0 (0–0) A | 0.0 ± 0.0 | 0.0 (0–0) A | 1.1 ± 3.1 | 0.0 (0–12) A | 10.98 | 0.1041 |
266 |  | 0.0 ± 0.0 | 0.0 (0—0) A | 0.0 ± 0.0 | 0.0 (0–0) A | 1.2 ± 3.6 | 0.0 (0–14) A | 8.56 | 0.1138 |
273 |  | 0.0 ± 0.0 | 0.0 (0—0) A | 0.0 ± 0.0 | 0.0 (0–0) A | 0.9 ± 3.1 | 0.0 (0–12) A | 6.28 | 0.1433 |
280 |  | 0.0 ± 0.0 | 0.0 (0–0) A | 0.0 ± 0.0 | 0.0 (0–0) A | 0.4 ± 0.7 | 0.0 (0–2) A | 8.57 | 0.0738 |
287 |  | 0.0 ± 0.0 | 0.0 (0–0) A | 0.0 ± 0.0 | 0.0 (0–0) A | 0.2 ± 0.4 | 0.0 (0–1) A | 6.29 | 0.0632 |
294 |  | 0.1 ± 0.3 | 0.0 (0–1) A | 0.0 ± 0.0 | 0.0 (0–0) A | 0.5 ± 0.7 | 0.0 (0–2) A | 10.42 | 0.1555 |
301 |  | 0.5 ± 0.7 | 0.0 (0–2) A | 0.5 ± 1.1 | 0.0 (0–4) A | 0.7 ± 0.8 | 1.0 (0–2) A | 1.65 | 0.4386 |
308 |  | 0.9 ± 0.8 | 1.0 (0–2) A | 0.7 ± 0.9 | 0.0 (0–2) A | 1.8 ± 1.5 | 2.0 (0–5) A | 6.24 | 0.0144 |
315 |  | 1.0 ± 0.8 | 1.0 (0–2) A | 1.2 ± 0.9 | 1.0 (0–3) A | 2.5 ± 1.9 | 2.0 (0–5) A | 5.54 | 0.0626 |
322 |  | 2.5 ± 2.1 | 2.0 (0–4) A | 1.4 ± 1.5 | 1.0 (0–5) A | 2.5 ± 3.0 | 2.0 (0–12) A | 2.39 | 0.3031 |
329 |  | 3.7 ± 1.7 | 4.0 (0–6) A | 2.3 ± 2.9 | 2.0 (0–12) A | 2.4 ± 1.9 | 2.0 (0–6) AB | 7.64 | 0.0719 |
336 |  | 10.1 ± 8.0 | 9.0 (1–24) A | 7.8 ± 5.9 | 5.0 (0–20) A | 8.1 ± 6.9 | 9.0 (0–19) A | 0.69 | 0.7084 |
343 |  | 15.4 ± 8.0 | 17.0 (0–26) A | 14.6 ± 5.7 | 15.0 (4–24) A | 15.5 ± 8.0 | 14.0 (5–32) A | 0.38 | 0.8261 |