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Table 2 Adverse reactions measured throughout treatment

From: Improving access to melarsomine therapy: treating canine heartworm infection in a high-volume, outpatient community clinic setting

Adverse reactions observed in the clinic by VT/VA following a melarsomine injection

Behavioral

Salivation, panting, trembling, whining, reluctance to move

Local injection site

Pain, injection site swelling

Respiratory

Onset in labored breathing/dyspnea

Gastrointestinal

Vomiting, diarrhea

Immediate hypersensitivity

Pale mucous membranes, hives, facial swelling, acute collapse

Adverse reactions observed by the owner up to 10 days following a melarsomine injection

Behavioral

Panting, trembling, whining, lethargy, reluctance to move

Local injection site

Pain, injection site swelling, redness, abscess

Respiratory

Abnormally rapid breathing, onset in labored breathing, coughing, or coughing up blood

Gastrointestinal

Vomiting, diarrhea, decreased appetite

  1. Modified from Maxwell et al. [12]. Adverse reactions were recorded as presence/absence