Fig. 3
From: Construction of luciferase-expressing Neospora caninum and drug screening
The non-effects of luciferase expression on the pathogenicity of N. caninum in mice. A Survival curves of mice. 1.5 × 107 tachyzoites were inoculated intraperitoneally into BALB/c mice (5 mice per group), and the survival of mice was observed over a 30-day period. B Parasite burden in the brain. After 30 days of infection, the parasite burden of surviving mice was detected by qPCR. The qPCR assay was performed in triplicate. Results are shown as mean ± SD. Survival curves were analyzed using the log-rank (Mantel–Cox) test, and qPCR results were analyzed by t-test in GraphPad Prism (San Diego, CA, USA). ns: no difference, P > 0.05