Day | Control group | SC1S | SC2S | Mean efficacy of fluralaner 5% (%) | DAT | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Mean | SEM | Mean | SEM | Mean | SEM | ||||||
Pre | 32.50 | 4.36 | a | 32.58 | 3.93 | a | 34.67 | 6.37 | a | ||
3 | 25.83 | 3.15 | a | 0.08 | 0.08 | b | 0.17 | 0.11 | b | 99.5 | 3 |
7 | 4.67 | 1.12 | a | 0.00 | 0.00 | a | 0.00 | 0.00 | a | 100.0 | 7 |
14 | 6.00 | 1.54 | a | 0.00 | 0.00 | b | 0.00 | 0.00 | b | 100.0 | 14 |
28 | 21.25 | 4.62 | a | 0.00 | 0.00 | b | 0.00 | 0.00 | b | 100.0 | 28 |
40 | 20.08 | 3.16 | a | 2.25 | 0.84 | b | 0.08 | 0.08 | b | 94.2 | 40 |
48 | 21.17 | 3.95 | a | 0.00 | 0.00 | b | 0.00 | 0.00 | b | 100.0 | 8 |
56 | 21.75 | 4.00 | a | 0.00 | 0.00 | b | 0.00 | 0.00 | b | 100.0 | 16 |
70 | 12.08 | 2.60 | a | 0.00 | 0.00 | b | 0.00 | 0.00 | b | 100.0 | 30 |
84 | 5.50 | 0.69 | a | 0.08 | 0.08 | a | 0.00 | 0.00 | a | 99.2 | 44 |
91 | 9.08 | 1.85 | a | 0.00 | 0.00 | b | 0.00 | 0.00 | b | 100.0 | 7 |
98 | 4.17 | 0.67 | a | 0.00 | 0.00 | a | 0.00 | 0.00 | a | 100.0 | 14 |
112 | 23.67 | 5.56 | a | 0.00 | 0.00 | b | 0.00 | 0.00 | b | 100.0 | 28 |
126 | 15.83 | 2.47 | a | 0.00 | 0.00 | b | 0.00 | 0.00 | b | 100.0 | 42 |
140 | 4.50 | 1.00 | a | 0.17 | 0.11 | a | 0.08 | 0.08 | a | 97.2 | 56 |
154 | 7.08 | 1.81 | a | 0.17 | 0.17 | b | 0.17 | 0.17 | b | 97.6 | 70 |
168 | 10.33 | 1.89 | a | 0.25 | 0.18 | b | 0.25 | 0.18 | b | 97.6 | 84 |
182 | 13.42 | 2.49 | a | 0.08 | 0.08 | b | 0.08 | 0.08 | b | 99.4 | 98 |
189 | 18.17 | 2.57 | a | 0.08 | 0.08 | b | 0.00 | 0.00 | b | 100.0 | 7** |
196 | 11.67 | 1.56 | a | 0.08 | 0.08 | b | 0.00 | 0.00 | b | 100.0 | 14 |
210 | 10.17 | 1.89 | a | 0.08 | 0.08 | b | 0.00 | 0.00 | b | 100.0 | 28 |
224 | 7.17 | 0.98 | a | 1.17 | 0.39 | b | 0.00 | 0.00 | b | 100.0 | 42 |
231 | 8.42 | 1.66 | a | 8.17 | 1.38 | a | 0.00 | 0.00 | b | 100.0 | 7 |
238 | 12.50 | 2.86 | a | 9.17 | 1.32 | a | 0.00 | 0.00 | b | 100.0 | 14 |
252 | 13.17 | 2.10 | a | 9.75 | 1.73 | a | 0.00 | 0.00 | b | 100.0 | 28 |
266 | 3.17 | 0.49 | a | 1.50 | 0.38 | a | 0.00 | 0.00 | a | 100.0 | 42 |
273 | 2.92 | 0.58 | a | 0.75 | 0.25 | a | 0.00 | 0.00 | a | 100.0 | 7 |
280 | 8.25 | 1.90 | a | 1.33 | 0.45 | b | 0.00 | 0.00 | b | 100.0 | 14 |
294 | 10.33 | 1.85 | a | 2.75 | 0.75 | b | 0.00 | 0.00 | b | 100.0 | 28 |
308 | 7.67 | 1.16 | a | 2.83 | 0.63 | ab | 0.58 | 0.23 | b | 92.4 | 42 |
322 | 8.08 | 1.63 | a | 9.17 | 1.71 | a | 0.33 | 0.19 | b | 95.9 | 56 |
336 | 8.67 | 2.20 | a | 7.08 | 1.27 | ab | 2.58 | 0.71 | b | 70.2 | 70 |