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Table 5 Percent of motility inhibition induced by BZDs and ABZSO at a dose of 10 µM on an ABZ-resistant isolate of Fasciola hepatica adults after 48 and 72 h of treatment

From: New benzimidazole derivative compounds with in vitro fasciolicidal properties

Compound

% Adult motility inhibition

48 h

% Adult motility inhibition

72 h

C− (DMSO 0.5%)

27.8

31.5

ABZO

25.0

25.0

BZD31

35.7

38.1

BZD46

28.6

28.6

BZD56

53.0

51.5

BZD59

46.7

60.0

  1. ABZ, albendazole; ABZO, albendazole sulfoxide; C−, negative control