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Fig. 5 | Parasites & Vectors

Fig. 5

From: mmu-miR-374b-5p modulated inflammatory factors via downregulation of C/EBP β/NF-κB signaling in Kupffer cells during Echinococcus multilocularis infection

Fig. 5

Production of proinflammatory factors was inhibited in KCs treated with ESPs. A mRNA expression levels of inflammatory factors in KCs from Echinococcus multilocularis-infected mice at 2 months post-infection. B mRNA expression levels of miR-374b-5p, (C) C/EBP β and (E) inflammatory factors in the ESP-treated KCs. D Protein expression levels of NF-κBp65 and p-NF-κBp65 were detected in the ESP-treated KCs. F Protein expression levels of inflammatory factors were detected in the ESP-treated KCs. Corresponding p value was calculated between experimental group and control group by t-test, *p < 0.05, **p < 0.01, ***p < 0.001. 2 M-KC-C: KCs from mice treated with PBS for 2 months, 2 M-KC-E: KCs from mice 2 months post-infection with E. multilocularis, ESP: excretory/secretory products

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Parasites & Vectors

ISSN: 1756-3305

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