Table 1 Nine epitope-rich domains selected from three proteins AP33, AP65, and α-actinin
Antigen | Position | Antigenic determinant |
|---|---|---|
AP33 | 169–290 50–115 | LTYEAAYATTQAGLGQSTVVGIGGDPFAGQLHTDVIKRFAADPQTEGIILIGE IGGTSEEDAAEWIAKTKLTQEKPVVAFIAGATAPPGKRMGHAGAIVSGGKGTAEGKYKALEAAGVRIAR VHPKKAGKIIAGLPIFKNMKEVVKRTDANASLIFVPAPGAAAACIEAAEAGMGLVVCITEHIPQHD |
AP65 | 60–160 320–370 420–480 | KDEQAARIRRQFELMPTPLLKYIFLANEREKNSQSFW RFLFTHPPEETMPILYTPTVGEACQKWATHRQSYRGIYITPEDSGKIKDILRNYPRQDIRCIVV IANLIVDMTVSRGGITKEQAFKNIIMFDHRGMVHAGRKDLYDFNKPYMHDM NPTPKAEATPHDVYLWSNGKALCATGSPFPAEQVNGRKVITAQANNSWIFPAVGYALVTTK |
α-actinin | 500–580 220–330 740–800 620–665 | IAFKEEVLAISGELRERRTQFLAKQAEAPTKR EHVNEIDPIFDGLEKDSLHLRVNHSPTEIRNVYAVTLQHIITELNKIFE EKSVVTQVAEFFHFFASESKIAAMADKIKRTVAIQKQIDELKNTYIEDAKAAI EKMTVEDEKLKADDYEKTIPGIRGKLASVISYNRDIRPEIVDHRAKAMRSWAALVTKC EELTPIYEDLEKDQLHLEITSTPASINIFFENLIAHIDTLVKEIDAAIAAAKGLEISEEEL ENLASLDGFAEKIQALQDPYNELVEFKLNYKVTYTYSDATGELDQA |