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Table 1 Model parameters

From: Modelling the potential of focal screening and treatment as elimination strategy for Plasmodium falciparum malaria in the Peruvian Amazon Region

Parameters Symbol Value Source
Baseline model parameters    
  Mosquito density (ratio female mosquitoes/humans) m 75 Assumed value within published range
  Human feeding rate, bites per mosquito per day a 0.035 - 0.32 Monthly estimations from fitting cohort data; values within published range
Mean: 0.088
  Susceptibility of an individual to infection after being bitten by an infectious mosquito b 0.05 Estimation using cohort and published data
  Mosquito susceptibility to infection after biting an infectious individual c 0.41 Published data
  Duration of human latent period for Pf* in d]’ cays (l = l 1 + l 2 ) l 21 Published data
  Duration from sporozoite inoculation to development of blood asexual parasites in days l 1 11 Published data
  Duration from asexual blood stage infection to development of gametocytes in days l 2 10 Published data
  Duration of mosquito latent period in days n 11 Published data
  Daily human mortality rate h 0.00005 Published data
  Daily mosquito mortality rate g 0.16 Published data
  Fraction of symptomatic infections y 0.65 Cohort data
  Treatment effectiveness ε 0.98 Published data
  Duration of infectious period in treated humans with ACT (in days) r 1 14 Published data
  Duration of infectious period in untreated humans in days (r 2 = r 2a + r 2b ) r 2 200 Published data
  Duration of presence of blood asexual parasites in untreated humans in days r 2a 80 Published data
  Duration of infectious period in untreated humans after clearance of blood asexual parasites in days r 2b 120 Published data
FSAT parameters    
  Coverage of FSAT Δ 1 Assumption
  Duration of FSAT in days v 1 Assumption
  Sensitivity of microscopy for detecting Pf* asexual stages s 1a 0.5 Published data
  Sensitivity of microscopy for detecting Pf*gametocytes s 1g 0.1 Published data
  Sensitivity of highly sensitive diagnostic tests for detecting asexual stages s 2a 0.95 Assumption
  Sensitivity of highly sensitive diagnostic tests for detecting gametocytes s 2g 0.8 Assumption
  1. *Pf = P. falciparum.