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Table 5 The percentage of T lymphocyte sub-populations in the spleen of Acanthamoeba spp.-infected immunosuppressed mice and control mice with low immunity

From: Changes in the immune system in experimental acanthamoebiasis in immunocompetent and immunosuppressed hosts

Parameter/group    Group AS (n = 10) Group CS (n = 6) Mann-Whitney U-test
CD3+ (T lymphocytes)% 8 dpi AM ± SD 29.21 ± 3.23 33.99 ± 2.60 U = 23, P = 0.04
Median 29.78 34.63
Range 24.75–33.23 30.94–36.46
16 dpi AM ± SD 32.77 ± 1.62 36.07 ± 7.97 U = 14, P = 0.83
Median 33.03 33.63
Range 30.08–34.27 28.83–49.13
24 dpi AM ± SD 31.65 ± 11.57 22.96 ± 3.10 U = 22, P = 0.05
Median 28.23 22.73
Range 21.76–51.73 19.78–26.09
CD4+ % 8 dpi AM ± SD 77.37 ± 1.17 70.74 ± 1.67 U = 25, P = 0.01
Median 77.24 70.59
Range 74.98–79.46 68.14–73.33
16 dpi AM ± SD 74.91 ± 1.56 77.40 ± 1.43 U = 22, P = 0.06
Median 75.60 77.36
Range 72.70–76.26 75.27–78.73
24 dpi AM ± SD 72.14 ± 6.06 76.55 ± 5.98 U = 21, P = 0.14
Median 74.18 78.70
Range 62.53–78.17 66.38–81.85
CD8+ % 8 dpi AM ± SD 17.74 ± 1.39 21.80 ± 0.57 U = 25, P = 0.01
Median 17.14 21.58
Range 16.14–19.47 21.16–22.62
16 dpi AM ± SD 14.31 ± 8.43 16.86 ± 2.67 U = 13, P = 0.99
Median 16.72 16.40
Range 0.15–22.62 13.85–20.15
24 dpi AM ± SD 14.98 ± 2.60 17.89 ± 1.19 U = 21, P = 0.09
Median 14.64 17.37
Range 12.23–18.69 16.93–19.75
CD4-/CD8- % 8 dpi AM ± SD 3.70 ± 0.87 5.69 ± 1.60 U = 22, P = 0.05
Median 3.67 6.10
Range 2.62–4.90 3.29–7.18
16 dpi AM ± SD 9.27 ± 8.06 4.10 ± 1.22 U = 21, P = 0.09
Median 6.67 4.48
Range 4.02–23.5 2.45–5.54
24 dpi AM ± SD 7.22 ± 3.61 5.97 ± 2.54 U = 17, P = 0.41
Median 6.20 4.93
Range 4.13–13.45 3.81–10.3
CD4+/CD8+ % 8 dpi AM ± SD 0.43 ± 0.06 0.43 ± 0.09 U = 14, P = 0.83
Median 0.41 0.38
Range 0.36–0.52 0.38–0.61
16 dpi AM ± SD 0.52 ± 0.29 0.57 ± 0.13 U = 12, P = 0.99
Median 0.65 0.58
Range 0.01–0.70 0.38–0.72
24 dpi AM ± SD 0.34 ± 0.09 0.48 ± 0.15 U = 19, P = 0.21
Median 0.38 0.44
Range 0.21–0.42 0.29–0.67
  1. Abbreviations: Group A, immunocompetent infected group; Group C, immunocompetent control group; Group AS immunosuppressed infected group; Group CS, immunosuppressed non-infected group; AM, arithmetic mean; SD, standard deviation