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  1. Research

    Heartworm-associated respiratory disease (HARD) induced by immature adult Dirofilaria immitis in cats

    A controlled, blind research study was conducted to define the initial inflammatory response and lung damage associated with the death of immature adult Dirofilaria immitis in cats as compared with cats developin...

    A. Ray Dillon, Byron L. Blagburn, Michael Tillson, William Brawner, Betsy Welles, Calvin Johnson, Russell Cattley, Pat Rynders and Sharron Barney

    Parasites & Vectors 2017 10(Suppl 2):514

    Published on: 9 November 2017

    This article is part of a Supplement: Volume 10 Supplement 2

  2. Research

    Shifting the paradigm in Dirofilaria immitis prevention: blocking transmission from mosquitoes to dogs using repellents/insecticides and macrocyclic lactone prevention as part of a multimodal approach

    This study assessed the influence of a topical ectoparasiticide (dinotefuran-permethrin-pyriproxyfen, DPP, Vectra® 3D, Ceva Animal Health) combined with a macrocyclic lactone (milbemycin oxime, MBO, Intercepto...

    John W. McCall, Marie Varloud, Elizabeth Hodgkins, Abdelmoneim Mansour, Utami DiCosty, Scott McCall, James Carmichael, Ben Carson and Justin Carter

    Parasites & Vectors 2017 10(Suppl 2):525

    Published on: 9 November 2017

    This article is part of a Supplement: Volume 10 Supplement 2

  3. Research

    Prevalence of tick-borne pathogens in questing Ixodes ricinus ticks in urban and suburban areas of Switzerland

    Throughout Europe, Ixodes ricinus transmits numerous pathogens. Its widespread distribution is not limited to rural but also includes urbanized areas. To date, comprehensive data on pathogen carrier rates of I. r...

    Corinne P. Oechslin, Daniel Heutschi, Nicole Lenz, Werner Tischhauser, Olivier Péter, Olivier Rais, Christian M. Beuret, Stephen L. Leib, Sergei Bankoul and Rahel Ackermann-Gäumann

    Parasites & Vectors 2017 10:558

    Published on: 9 November 2017

  4. Research

    Incidence of dengue and chikungunya viruses in mosquitoes and human patients in border provinces of Vietnam

    Dengue virus remains a major threat in Vietnam, while chikungunya virus is expected to become one. Surveillance was conducted from 2012 to 2014 in Vietnam to assess the presence of dengue and chikungunya virus...

    Kim Lien Pham Thi, Laurence Briant, Laurent Gavotte, Pierrick Labbe, Marco Perriat-Sanguinet, Emmanuel Cornillot, Trong Duoc Vu, Thi Yen Nguyen, Vu Phong Tran, Van Soai Nguyen, Christian Devaux, Aneta Afelt, Chi Cuong Tran, Thi Nga Phan, Nhu Duong Tran and Roger Frutos

    Parasites & Vectors 2017 10:556

    Published on: 9 November 2017

  5. Research

    Prevalence and epidemiology of canine and feline heartworm infection in Taiwan

    Heartworm, Dirofilaria immitis, has long been recognized in Taiwanese dogs but feline heartworm infection has been largely overlooked by veterinarians and pet owners. The main goal of this study was to determine ...

    Ta-Li Lu, Jun-Yue Wong, Ta-Lun Tan and Yong-Wei Hung

    Parasites & Vectors 2017 10(Suppl 2):484

    Published on: 9 November 2017

    This article is part of a Supplement: Volume 10 Supplement 2

  6. Research

    The progression of heartworm associated respiratory disease (HARD) in SPF cats 18 months after Dirofilaria immitis infection

    Heartworm-associated respiratory disease (HARD) in cats is induced by the arrival and death of immature adult Dirofilaria immitis in the pulmonary system and is indistinguishable from mature adult heartworm infec...

    A. Ray Dillon, Bryon L. Blagburn, Michael Tillson, William Brawner, Betsy Welles, Calvin Johnson, Russell Cattley, Pat Rynders and Sharron Barney

    Parasites & Vectors 2017 10(Suppl 2):533

    Published on: 9 November 2017

    This article is part of a Supplement: Volume 10 Supplement 2

  7. Research

    Farm-level risk factors for Fasciola hepatica infection in Danish dairy cattle as evaluated by two diagnostic methods

    The prevalence of bovine fasciolosis in Denmark is increasing but appropriate guidelines for control are currently lacking. In order to help develop a control strategy for liver fluke, a risk factor study of f...

    Nao Takeuchi-Storm, Matthew Denwood, Tina Vicky Alstrup Hansen, Tariq Halasa, Erik Rattenborg, Jaap Boes, Heidi Larsen Enemark and Stig Milan Thamsborg

    Parasites & Vectors 2017 10:555

    Published on: 9 November 2017

  8. Research

    A statistical approach for evaluating the effectiveness of heartworm preventive drugs: what does 100% efficacy really mean?

    Initial studies of heartworm preventive drugs all yielded an observed efficacy of 100% with a single dose, and based on these data the US Food and Drug Administration (FDA) required all products to meet this s...

    Anand N. Vidyashankar, Pablo D. Jimenez Castro and Ray M. Kaplan

    Parasites & Vectors 2017 10(Suppl 2):516

    Published on: 9 November 2017

    This article is part of a Supplement: Volume 10 Supplement 2

  9. Research

    Sequence analysis and characterization of pyruvate kinase from Clonorchis sinensis, a 53.1-kDa homopentamer, implicated immune protective efficacy against clonorchiasis

    Clonorchis sinensis, the causative agent of clonorchiasis, is classified as one of the most neglected tropical diseases and affects more than 15 million people globally. This hepatobil...

    Tingjin Chen, Hongye Jiang, Hengchang Sun, Zhizhi Xie, Pengli Ren, Lu Zhao, Huimin Dong, Mengchen Shi, Zhiyue Lv, Zhongdao Wu, Xuerong Li, Xinbing Yu, Yan Huang and Jin Xu

    Parasites & Vectors 2017 10:557

    Published on: 9 November 2017

  10. Research

    Production and characterization of monoclonal antibodies against Encephalitozoon intestinalis and Encephalitozoon sp. spores and their developmental stages

    Microsporidia are intracellular obligate parasites traditionally associated with immunosuppressed patients; their detection in immunocompetent patients has increased, highlighting their possible importance as ...

    Fernando Izquierdo, Hercules Moura, Fernando Jorge Bornay-Llinares, Rama Sriram, Carolina Hurtado, Ángela Magnet, Soledad Fenoy, Govinda Visvesvara and Carmen del Aguila

    Parasites & Vectors 2017 10:560

    Published on: 9 November 2017

  11. Review

    Cardiopulmonary and inflammatory biomarkers in heartworm disease

    In heartworm disease, several biomarkers of cardiopulmonary injury and inflammatory activity have been studied during the recent years. D-dimer is a fibrin degradation product present after a clot is degraded,...

    Elena Carretón, Rodrigo Morchón and José Alberto Montoya-Alonso

    Parasites & Vectors 2017 10(Suppl 2):534

    Published on: 9 November 2017

    This article is part of a Supplement: Volume 10 Supplement 2

  12. Research

    Efficacy of 10% imidacloprid + 2.5% moxidectin topical solution (Advantage Multi® for Dogs) for the prevention of heartworm disease and infection all month long

    Prior work has shown that the levels of moxidectin in dogs treated with Advantage Multi® for Dogs (Bayer Animal Health) remain at a high plasma concentration for the full month after application. The objective...

    Dwight D. Bowman, Cameon M. Ohmes, Joseph A. Hostetler, Daniel J. Keil, Terry L. Settje and Samuel D. Charles

    Parasites & Vectors 2017 10(Suppl 2):478

    Published on: 9 November 2017

    This article is part of a Supplement: Volume 10 Supplement 2

  13. Research

    Evaluation of Dirofilaria immitis antigen detection comparing heated and unheated serum in dogs with experimental heartworm infections

    To evaluate whether heated serum allows for earlier detection of Dirofilaria immitis antigen, dogs with experimental D. immitis infections underwent weekly blood sampling to compare antigen results using both hea...

    James Carmichael, Scott McCall, Utami DiCosty, Abdelmoneim Mansour and Linda Roycroft

    Parasites & Vectors 2017 10(Suppl 2):486

    Published on: 9 November 2017

    This article is part of a Supplement: Volume 10 Supplement 2

  14. Research

    Acute phase proteins and markers of oxidative stress to assess the severity of the pulmonary hypertension in heartworm-infected dogs

    Canine heartworm infection is characterized by pulmonary endarteritis and pulmonary hypertension (PH). The aim of the present study was to evaluate the relationship between PH with the concentrations of differ...

    Elena Carretón, José Joaquín Cerón, Silvia Martínez-Subiela, Asta Tvarijonaviciute, Alicia Caro-Vadillo and José Alberto Montoya-Alonso

    Parasites & Vectors 2017 10(Suppl 2):477

    Published on: 9 November 2017

    This article is part of a Supplement: Volume 10 Supplement 2

  15. Meeting report

    A European network for food-borne parasites (Euro-FBP): meeting report on ‘Analytical methods for food-borne parasites in human and veterinary diagnostics and in food matrices’

    Food-borne parasites (FBPs) are a neglected topic in food safety, partly due to a lack of awareness of their importance for public health, especially as symptoms tend not to develop immediately after exposure....

    Christian Klotz, Barbara Šoba, Miha Skvarč, Sarah Gabriël and Lucy J. Robertson

    Parasites & Vectors 2017 10:559

    Published on: 9 November 2017

  16. Research

    Validation of immune complex dissociation methods for use with heartworm antigen tests

    Antigen testing is routinely used to diagnose canine Dirofilaria immitis infections. Immune complex dissociation (ICD) methods, which were employed in the original heartworm antigen tests to release antigen that ...

    Melissa J. Beall, Andrea Arguello-Marin, Jan Drexel, Jiayou Liu, Ramaswamy Chandrashekar and A. Rick Alleman

    Parasites & Vectors 2017 10(Suppl 2):481

    Published on: 9 November 2017

    This article is part of a Supplement: Volume 10 Supplement 2

  17. Research

    Comparative evaluation of commercially available point-of-care heartworm antigen tests using well-characterized canine plasma samples

    Dirofilaria immitis is a worldwide parasite that is endemic in many parts of the United States. There are many commercial assays available for the detection of D. immitis antigen, one ...

    Lindsay A. Starkey, Joy V. Bowles, Mark E. Payton and Byron L. Blagburn

    Parasites & Vectors 2017 10(Suppl 2):475

    Published on: 9 November 2017

    This article is part of a Supplement: Volume 10 Supplement 2

  18. Research

    Genetic profiles of ten Dirofilaria immitis isolates susceptible or resistant to macrocyclic lactone heartworm preventives

    For dogs and cats, chemoprophylaxis with macrocyclic lactone (ML) preventives for heartworm disease is widely used in the United States and other countries. Since 2005, cases of loss of efficacy (LOE) of heart...

    Catherine Bourguinat, Kathy Keller, Jianguo Xia, Pierre Lepage, Tom L. McTier, Debra J. Woods and Roger K. Prichard

    Parasites & Vectors 2017 10(Suppl 2):504

    Published on: 9 November 2017

    This article is part of a Supplement: Volume 10 Supplement 2

  19. Research

    Effect of heartworm disease and heartworm-associated respiratory disease (HARD) on the right ventricle of cats

    Dirofilaria immitis infection occurs in dogs and cats, both of which species are clinically affected by mature adult infections. Cats are uniquely affected by immature-adult infections...

    Randolph L. Winter, A. Ray Dillon, Russell C. Cattley, Byron L. Blagburn, D. Michael Tillson, Calvin M. Johnson, William R. Brawner, Elizabeth G. Welles and Sharon Barney

    Parasites & Vectors 2017 10(Suppl 2):492

    Published on: 9 November 2017

    This article is part of a Supplement: Volume 10 Supplement 2

  20. Research

    Evaluation of the efficacy of ProHeart® 6 (moxidectin) against a resistant isolate of Dirofilaria immitis (JYD-34) in dogs

    In a previous study, it was demonstrated that ProHeart® 6 (PH6) (moxidectin, Zoetis) provided only about 20% efficacy in a small six-dog study against a macrocyclic lactone –resistant Dirofilaria immitis isolate ...

    Dwight D. Bowman, Tom L. McTier, Eric L. Adams, Sean P. Mahabir, Joyce A. Login, Tara Bidgood and Debra J. Woods

    Parasites & Vectors 2017 10(Suppl 2):502

    Published on: 9 November 2017

    This article is part of a Supplement: Volume 10 Supplement 2

  21. Research

    The impact of temperature and Wolbachia infection on vector competence of potential dengue vectors Aedes aegypti and Aedes albopictus in the transmission of dengue virus serotype 1 in southern Taiwan

    We evaluated the impact of temperature and Wolbachia infection on vector competence of the local Aedes aegypti and Ae. albopictus populations of southern Taiwan in the laboratory.

    Cheng-Hui Tsai, Tien-Huang Chen, Cheo Lin, Pei-Yun Shu, Chien-Ling Su and Hwa-Jen Teng

    Parasites & Vectors 2017 10:551

    Published on: 7 November 2017

  22. Research

    Prevalence of Bartonella spp. by culture, PCR and serology, in veterinary personnel from Spain

    The genus Bartonella includes fastidious, facultative intracellular bacteria mainly transmitted by arthropods and distributed among mammalian reservoirs. Bartonella spp. implicated as etiological agents of zoonos...

    José A. Oteo, Ricardo Maggi, Aránzazu Portillo, Julie Bradley, Lara García-Álvarez, Montserrat San-Martín, Xavier Roura and Edward Breitschwerdt

    Parasites & Vectors 2017 10:553

    Published on: 7 November 2017

  23. Research

    Plasmodium reichenowi EBA-140 merozoite ligand binds to glycophorin D on chimpanzee red blood cells, shedding new light on origins of Plasmodium falciparum

    All symptoms of malaria are caused by the intraerythrocytic proliferation of Plasmodium merozoites. Merozoites invade erythrocytes using multiple binding ligands that recognise specific surface receptors. It has ...

    Agata Zerka, Radoslaw Kaczmarek, Marcin Czerwinski and Ewa Jaskiewicz

    Parasites & Vectors 2017 10:554

    Published on: 7 November 2017

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