Tenter AM, Heckeroth AR, Weiss LM. Toxoplasma gondii: from animals to humans. Int J Parasitol. 2000;30:1217–58.
Article
CAS
PubMed
PubMed Central
Google Scholar
Dubey JP. Toxoplasmosis of animals and humans. 2nd ed. Boca Raton: CRC Press; 2010.
Google Scholar
Dubey JP. History of the discovery of the life cycle of Toxoplasma gondii. Int J Parasitol. 2009;39:877–82.
Article
CAS
PubMed
Google Scholar
Pappas G, Roussos N, Falagas ME. Toxoplasmosis snapshots: global status of Toxoplasma gondii seroprevalence and implications for pregnancy and congenital toxoplasmosis. Int J Parasitol. 2009;39:1385–94.
Article
PubMed
Google Scholar
Goyette S, Cao ZR, Libman M, Ndao M, Ward BJ. Seroprevalence of parasitic zoonoses and their relationship with social factors among the Canadian Inuit in Arctic regions. Diagn Microbiol Infect Dis. 2014;78:404–10.
Article
PubMed
Google Scholar
Jenkins EJ, Castrodale LJ, de Rosemond SJC, Dixon BR, Elmore SA, Gesy KM, et al. Tradition and transition: parasitic zoonoses of people and animals in Alaska, Northern Canada, and Greenland. In: Rollinson D, editor., et al., Advances in parasitology. Academic Press; 2013. p. 33–204.
Google Scholar
Messier V, Levesque B, Proulx JF, Rochette L, Libman MD, Ward BJ, et al. Seroprevalence of Toxoplasma gondii among Nunavik Inuit (Canada). Zoonoses Public Health. 2009;56:188–97.
Article
CAS
PubMed
Google Scholar
Ducrocq J, Lévesque B, Lemire M, de Serres G. Zoonotic and gastrointestinal diseases. Nunavik Inuit health survey 2017 Qanuilirpitaa? How are we now?. Quebec: Nunavik regional board of health and social services (NRBHSS) & Institut national de santé publique du Québec (INSPQ); 2021.
Ducrocq J, Ndao M, Yansouni CP, Proulx J-F, Mondor M, Hamel D, et al. Epidemiology associated with the exposure to Toxoplasma gondii in Nunavik’s Inuit population using the 2017 Qanuilirpitaa cross-sectional health survey. Zoonoses Public Health. 2021;68:803–14.
Article
PubMed
Google Scholar
Molan A, Nosaka K, Hunter M, Wang W. Global status of Toxoplasma gondii infection: systematic review and prevalence snapshots. Trop Biomed. 2019;36:898–925.
CAS
PubMed
Google Scholar
Jones JL, Kruszon-Moran D, Elder S, Rivera HN, Press C, Montoya JG, et al. Toxoplasma gondii Infection in the United States, 2011–2014. Am J Trop Med Hyg. 2018;98:551–7.
Article
PubMed
Google Scholar
Baker T, Flaig J, Shillingford M, Swain L, Wagner M. Ice road vets: Perspectives on the role of veterinarians in northern community health. Can Vet J. 2018;59:668–72.
PubMed
PubMed Central
Google Scholar
McDonald JC, Gyorkos TW, Alberton B, MacLean JD, Richer G, Juranek D. An outbreak of toxoplasmosis in pregnant women in northern Quebec. J Infect Dis. 1990;161:769–74.
Article
CAS
PubMed
Google Scholar
Reiling SJ, Dixon BR. Toxoplasma gondii: how an Amazonian parasite became an Inuit health issue. Can Commun Dis Rep. 2019;45:183–90.
Article
CAS
PubMed
PubMed Central
Google Scholar
Halliday JE, Meredith AL, Knobel DL, Shaw DJ, Bronsvoort BM, Cleaveland S. A framework for evaluating animals as sentinels for infectious disease surveillance. J R Soc Interface. 2007;4:973–84.
Article
PubMed
PubMed Central
Google Scholar
National research council (US) committee on animals as monitors of environmental hazards. Animals as sentinels of environmental health hazards. Washington (DC): National Academic Press (US); 1991.
Bachand N, Ravel A, Leighton P, Stephen C, Iqbal A, Ndao M, et al. Foxes (Vulpes vulpes) as sentinels for parasitic zoonoses, Toxoplasma gondii and Trichinella nativa, in the northeastern Canadian Arctic. Int J Parasitol Parasites Wildl. 2018;7:391–7.
Article
Google Scholar
Bouchard E, Elmore SA, Alisauskas RT, Samelius G, Gajadhar AA, Schmidt K, et al. Transmission dynamics of Toxoplasma Gondii in arctic foxes (Vulpes Lagopus): a long-term mark-recapture serologic study at Karrak Lake, Nunavut, Canada. J Wildl Dis. 2019;55:619–26.
Article
PubMed
Google Scholar
Sampasa-Kanyinga H, Lévesque B, Anassour-Laouan-Sidi E, Côté S, Serhir B, Ward BJ, et al. Zoonotic Infections in Native Communities of James Bay, Canada. Vector Borne Zoonotic Dis. 2012;12:473–81.
Article
PubMed
Google Scholar
Hersteinsson P, MacDonald DW. Interspecific competition and the geographical distribution of red and arctic foxes Vulpes Vulpes and Alopex lagopus. Oikos. 1992;64:505–15.
Article
Google Scholar
Pamperin N, Follmann E, Petersen B. Interspecific killing of an Arctic fox by a red fox at Prudhoe Bay, Alaska. Arctic. 2009;59.
Rinke A, Dethloff K. Simulated circum-arctic climate changes by the end of the 21st century. Glob Planet Change. 2008;62:173–86.
Article
Google Scholar
Bush E, Lemmen DS, Canada’s changing climate report; Government of Canada, Ottawa, ON; 2019.
Macri G, Sala M, Linder AM, Pettirossi N, Scarpulla M. Comparison of indirect fluorescent antibody test and modified agglutination test for detecting Toxoplasma gondii immunoglobulin G antibodies in dog and cat. Parasitol Res. 2009;105:35–40.
Article
PubMed
Google Scholar
Bastien P. Molecular diagnosis of toxoplasmosis. Trans R Soc Trop Med Hyg. 2002;96:S205–15.
Article
PubMed
Google Scholar
Gomez-Samblas M, Vilchez S, Racero JC, Fuentes MV, Osuna A. Quantification and viability assays of Toxoplasma gondii in commercial “Serrano” ham samples using magnetic capture real-time qPCR and bioassay techniques. Food Microbiol. 2015;46:107–13.
Article
CAS
PubMed
Google Scholar
Hill DE, Chirukandoth S, Dubey JP, Lunney JK, Gamble HR. Comparison of detection methods for Toxoplasma gondii in naturally and experimentally infected swine. Vet Parasitol. 2006;141:9–17.
Article
CAS
PubMed
Google Scholar
Opsteegh M, Langelaar M, Sprong H, den Hartog L, De Craeye S, Bokken G, et al. Direct detection and genotyping of Toxoplasma gondii in meat samples using magnetic capture and PCR. Int J Food Microbiol. 2010;139:193–201.
Article
CAS
PubMed
Google Scholar
Sharma R, Parker S, Al-Adhami B, Bachand N, Jenkins E. Comparison of tissues (heart vs. brain) and serological tests (MAT, ELISA and IFAT) for detection of Toxoplasma gondii in naturally infected wolverines (Gulo gulo) from the Yukon, Canada. Food Waterborne Parasitol. 2019;15:e00046.
Article
PubMed
PubMed Central
Google Scholar
Khan A, Dubey JP, Su C, Ajioka JW, Rosenthal BM, Sibley LD. Genetic analyses of atypical Toxoplasma gondii strains reveal a fourth clonal lineage in North America. Int J Parasitol. 2011;41:645–55.
Article
PubMed
PubMed Central
Google Scholar
Dubey JP, Murata FHA, Cerqueira-Cézar CK, Kwok OCH. Recent epidemiologic and clinical Toxoplasma gondii infections in wild canids and other carnivores: 2009–2020. Vet Parasitol. 2021;290:109337.
Article
CAS
PubMed
Google Scholar
Bachand N, Ravel A, Leighton P, Stephen C, Ndao M, Avard E, et al. Serological and molecular detection of Toxoplasma gondii in terrestrial and marine wildlife harvested for food in Nunavik, Canada. Parasit Vectors. 2019;12:155.
Article
PubMed
PubMed Central
Google Scholar
Galal L, Stragier C, Boumediene F, Hamidovic A, Maugrion O, Darde ML, et al. Combining spatial analysis and host population genetics to gain insights into the mode of transmission of a pathogen: the example of Toxoplasma gondii in mice. Infect Genet Evol. 2020;78:104142.
Article
CAS
PubMed
Google Scholar
Shapiro K, VanWormer E, Packham A, Dodd E, Conrad PA, Miller M. Type X strains of Toxoplasma gondii are virulent for southern sea otters (Enhydra lutris nereis) and present in felids from nearby watersheds. Proc Biol Sci. 2019;286:20191334.
CAS
PubMed
PubMed Central
Google Scholar
Su C, Shwab EK, Zhou P, Zhu XQ, Dubey JP. Moving towards an integrated approach to molecular detection and identification of Toxoplasma gondii. Parasitology. 2010;137:1–11.
Article
CAS
PubMed
Google Scholar
Gerhold RW, Saraf P, Chapman A, Zou X, Hickling G, Stiver WH, et al. Toxoplasma gondii seroprevalence and genotype diversity in select wildlife species from the southeastern United States. Parasit Vectors. 2017;10:508.
Article
PubMed
PubMed Central
Google Scholar
Ford JD, Bell T, Couture NJ. Perspectives on Canada’s North coast region. In: Lemmen DS, Warren FJ, James TS, Mercer Clarke CSL, editors. Canada’s marine coasts in a changing climate. Government of Canada, Ottawa: ON; 2016. p. 153–206.
Google Scholar
Gisbert Algaba I, Verhaegen B, Jennes M, Rahman M, Coucke W, Cox E, et al. Pork as a source of transmission of Toxoplasma gondii to humans: a parasite burden study in pig tissues after infection with different strains of Toxoplasma gondii as a function of time and different parasite stages. Int J Parasitol. 2018;48:555–60.
Article
PubMed
Google Scholar
Juránková J, Basso W, Neumayerová H, Baláž V, Jánová E, Sidler X, et al. Brain is the predilection site of Toxoplasma gondii in experimentally inoculated pigs as revealed by magnetic capture and real-time PCR. Food Microbiol. 2014;38:167–70.
Article
PubMed
Google Scholar
Koethe M, Straubinger RK, Pott S, Bangoura B, Geuthner AC, Daugschies A, et al. Quantitative detection of Toxoplasma gondii in tissues of experimentally infected turkeys and in retail turkey products by magnetic-capture PCR. Food Microbiol. 2015;52:11–7.
Article
CAS
PubMed
Google Scholar
Chevallier C, Gauthier G, Berteaux D. Age estimation of live arctic foxes Vulpes lagopus based on teeth condition. Wildlife Biol. 2017;1:1–6.
Article
Google Scholar
Mecca JN, Meireles LR, de Andrade Jr HF. Quality control of Toxoplasma gondii in meat packages: standardization of an ELISA test and its use for detection in rabbit meat cuts. Meat Sci. 2011;88:584–9.
Article
PubMed
Google Scholar
Viera AJ, Garrett JM. Understanding interobserver agreement: the kappa statistic. Fam Med. 2005;37:360–3.
PubMed
Google Scholar
Dubey JP, Sundar N, Gennari SM, Minervino AH, Farias NA, Ruas JL, et al. Biologic and genetic comparison of Toxoplasma gondii isolates in free-range chickens from the northern Para state and the southern state Rio Grande do Sul, Brazil revealed highly diverse and distinct parasite populations. Vet Parasitol. 2007;143:182–8.
Article
CAS
PubMed
Google Scholar
Sergeant ESG. Epitools epidemiological calculators. Ausvet. 2018. http://epitools.ausvet.com.au. Accessed 10 Sept 2021.
Bates D, Mächler M, Bolker B, Walker S. Fitting linear mixed-effects models using lme4. J Stat Softw. 2015;67:1–48.
Article
Google Scholar
R-Core-Team. R: a language and environment for statistical computing. Vienna, Austria. 2019. https://www.R-projectorg/.
Oberpriller J, de Souza LM, Pichler M. Fixed or random? On the reliability of mixed-effects models for a small number of levels in grouping variables. bioRxiv. 2021;35:329.
Google Scholar
Zuur AF, Ieno EN, Elphick CS. A protocol for data exploration to avoid common statistical problems. Methods Ecol Evol. 2010;1:3–14.
Article
Google Scholar
De Craeye S, Speybroeck N, Ajzenberg D, Darde ML, Collinet F, Tavernier P, et al. Toxoplasma gondii and Neospora caninum in wildlife: common parasites in Belgian foxes and Cervidae? Vet Parasitol. 2011;178:64–9.
Article
PubMed
Google Scholar
Herrmann DC, Maksimov P, Maksimov A, Sutor A, Schwarz S, Jaschke W, et al. Toxoplasma gondii in foxes and rodents from the German Federal States of Brandenburg and Saxony-Anhalt: seroprevalence and genotypes. Vet Parasitol. 2012;185:78–85.
Article
CAS
PubMed
Google Scholar
Gilbert AT, Fooks AR, Hayman DT, Horton DL, Muller T, Plowright R, et al. Deciphering serology to understand the ecology of infectious diseases in wildlife. EcoHealth. 2013;10:298–313.
Article
PubMed
Google Scholar
Robert-Gangneux F, Darde ML. Epidemiology of and diagnostic strategies for toxoplasmosis. Clin Microbiol Rev. 2012;25:264–96.
Article
CAS
PubMed
PubMed Central
Google Scholar
Szuma E, Germonpré M. Size of the lower carnassial in the arctic and the red fox from Late Pleistocene in Belgium compared to other ancient and extant populations. Mamm Res. 2020;65:127–39.
Article
Google Scholar
Gisbert AI, Verhaegen B, Jennes M, Rahman M, Coucke W, Cox E, et al. Pork as a source of transmission of Toxoplasma gondii to humans: a parasite burden study in pig tissues after infection with different strains of Toxoplasma gondii as a function of time and different parasite stages. Int J Parasitol. 2018;48:555–60.
Article
Google Scholar
Ferreira SCM, Torelli F, Klein S, Fyumagwa R, Karesh WB, Hofer H, et al. Evidence of high exposure to Toxoplasma gondii in free-ranging and captive African carnivores. Int J Parasitol Parasites Wildl. 2019;8:111–7.
Article
PubMed
Google Scholar
Sharma R, Parker S, Elkin B, Mulders R, Branigan M, Pongracz J, et al. Risk factors and prevalence of antibodies for Toxoplasma gondii in diaphragmatic fluid in wolverines (Gulo gulo) from the Northwest Territories, Canada. Food Waterborne Parasitol. 2019;15:e00056.
Article
PubMed
PubMed Central
Google Scholar
Rougier S, Montoya JG, Peyron F. Lifelong persistence of Toxoplasma cysts: a questionable dogma? Trends Parasitol. 2017;33:93–101.
Article
PubMed
Google Scholar
Blanchet C,Rochette L. Nutrition and Food Consumption among the Inuit of Nunavik. Nunavik Inuit health survey 2004, Qanuippitaa? How are we? Quebec: Institut national de santé publique du Québec (INSPQ) & Nunavik regional board of health and social services (NRBHSS); 2008.
Simon A, Rousseau AN, Savary S, Bigras-Poulin M, Ogden NH. Hydrological modelling of Toxoplasma gondii oocysts transport to investigate contaminated snowmelt runoff as a potential source of infection for marine mammals in the Canadian Arctic. J Environ Manag. 2013;127:150–61.
Article
Google Scholar
Mikaelian I, Boisclair J, Dubey JP, Kennedy S, Martineau D. Toxoplasmosis in beluga whales (Delphinapterus leucas) from the St Lawrence estuary: two case reports and a serological survey. J Comp Pathol. 2000;122:73–6.
Article
CAS
PubMed
Google Scholar
Shapiro K, Bahia-Oliveira L, Dixon B, Dumetre A, De Wit LA, VanWormer E, et al. Environmental transmission of Toxoplasma gondii: oocysts in water, soil and food. Food Waterborne Parasitol. 2019;15:e00049.
Article
PubMed
PubMed Central
Google Scholar
Bahia-Oliveira L, Gomez-Marin J, Shapiro K. Toxoplasma gondii. In: Rose JB, Jiménez-Cisneros B, editors. Global water pathogens project. Michigan State University, E. Lansing, MI, UNESCO; 2017.
Fung R, Manore AJW, Harper SL, Sargeant JM, Shirley J, Caughey A, et al. Clams and potential foodborne Toxoplasma gondii in Nunavut, Canada. Zoonoses Public Health. 2021;68:277–83.
Article
CAS
PubMed
Google Scholar
Miernyk KM, Bruden D, Parkinson AJ, Hurlburt D, Klejka J, Berner J, et al. Human Seroprevalence to 11 zoonotic pathogens in the U.S. Arctic, Alaska. Vector Borne Zoonotic Dis. 2019;19:563–75.
Article
PubMed
Google Scholar
Egeland GM. Inuit health survey 2007–2008. Nunavut. Ste-Anne-de-Bellevue, QC: McGill University; 2010.
Google Scholar
Egeland GM. Inuit health survey 2007–2008. Nunatsiavut. Ste-Anne-de-Bellevue, QC: McGill University; 2010.
Google Scholar
Egeland GM. Inuit health survey 2007–2008. Inuvialuit Settlement Region. Ste-Anne-de-Bellevue, QC: McGill University; 2010.
Google Scholar
Kutz SJ, Elkin BT, Panayi D, Dubey JP. Prevalence of Toxoplasma gondii antibodies in barren-ground caribou (Rangifer tarandus groenlandicus) from the Canadian Arctic. J Parasitol. 2001;87:439–42.
Article
CAS
PubMed
Google Scholar
Galal L, Schares G, Stragier C, Vignoles P, Brouat C, Cuny T, et al. Diversity of Toxoplasma gondii strains shaped by commensal communities of small mammals. Int J Parasitol. 2019;49:267–75.
Article
PubMed
Google Scholar
Gajadhar AA, Allen JR. Factors contributing to the public health and economic importance of waterborne zoonotic parasites. Vet Parasitol. 2004;126:3–14.
Article
PubMed
Google Scholar