Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71:209–49.
Article
PubMed
Google Scholar
Viganò L, Capussotti L, De Rosa G, De Saussure WO, Mentha G, Rubbia-Brandt L. Liver resection for colorectal metastases after chemotherapy: impact of chemotherapy-related liver injuries, pathological tumor response, and micrometastases on long-term survival. Ann Surg. 2013;258(5):731–40.
Article
PubMed
Google Scholar
Van Tong H, Brindley PJ, Meyer CG, Velavan TP. Parasite infection, carcinogenesis and human malignancy. EBioMedicine. 2017;15:12–23.
Article
PubMed
Google Scholar
Callejas BE, Martínez-Saucedo D, Terrazas LI. Parasites as negative regulators of cancer. Biosci Rep. 2018;38:BSR20180935.
Article
PubMed
PubMed Central
Google Scholar
Noya V, Bay S, Festari MF, García EP, Rodriguez E, Chiale C, et al. Mucin-like peptides from Echinococcus granulosus induce antitumor activity. Int J Oncol. 2013;43:775–84.
Article
CAS
PubMed
Google Scholar
Ranasinghe SL, Boyle GM, Fischer K, Potriquet J, Mulvenna JP, McManus DP. Kunitz type protease inhibitor EgKI-1 from the canine tapeworm Echinococcus granulosus as a promising therapeutic against breast cancer. PloS ONE. 2018;13:e0200433.
Article
PubMed
PubMed Central
CAS
Google Scholar
Salvador-Membreve DM, Jacinto SD, Rivera WL. Trichomonas vaginalis induces cytopathic effect on human lung alveolar basal carcinoma epithelial cell line A549. Exp Parasitol. 2014;147:33–40.
Article
CAS
PubMed
Google Scholar
Quan JH, Kang BH, Yang JB, Rhee YE, Noh HT, Choi IW, et al. Trichomonas vaginalis induces SiHa cell apoptosis by NF-κB inactivation via reactive oxygen species. Biomed Res Int. 2017;2017:3904870.
Article
PubMed
PubMed Central
CAS
Google Scholar
Aguilar-Guzmán L, Lobos-González L, Rosas C, Vallejos G, Falcón C, Sosoniuk E, et al. Human survivin and Trypanosoma cruzi calreticulin act in synergy against a murine melanoma in vivo. PloS ONE. 2014;9:e95457.
Article
PubMed
PubMed Central
CAS
Google Scholar
Ubillos L, Freire T, Berriel E, Chiribao ML, Chiale C, Festari MF, et al. Trypanosoma cruzi extracts elicit protective immune response against chemically induced colon and mammary cancers. Int J Cancer. 2016;138:1719–31.
Article
CAS
PubMed
Google Scholar
Pyo KH, Jung BK, Chai JY, Shin EH. Suppressed CD31 expression in sarcoma-180 tumors after injection with Toxoplasma gondii lysate antigen in BALB/c mice. Korean J Parasitol. 2010;48:171–4.
Article
CAS
PubMed
PubMed Central
Google Scholar
Baird JR, Fox BA, Sanders KL, Lizotte PH, Cubillos-Ruiz JR, Scarlett UK, et al. Avirulent Toxoplasma gondii generates therapeutic antitumor immunity by reversing immunosuppression in the ovarian cancer microenvironment. Cancer Res. 2013;73:3842–51.
Article
CAS
PubMed
PubMed Central
Google Scholar
Chen L, He Z, Qin L, Li Q, Shi X, Zhao S, et al. Antitumor effect of malaria parasite infection in a murine Lewis lung cancer model through induction of innate and adaptive immunity. PloS ONE. 2011;6:e24407.
Article
CAS
PubMed
PubMed Central
Google Scholar
Liu Q, Yang Y, Tan X, Tao Z, Adah D, Yu S, et al. Plasmodium parasite as an effective hepatocellular carcinoma antigen glypican-3 delivery vector. Oncotarget. 2017;8:24785–96.
Article
PubMed
PubMed Central
Google Scholar
Yang Y, Liu Q, Lu J, Adah D, Yu S, Zhao S, et al. Exosomes from Plasmodium-infected hosts inhibit tumor angiogenesis in a murine Lewis lung cancer model. Oncogenesis. 2017;6:e351.
Article
CAS
PubMed
PubMed Central
Google Scholar
Casaravilla C, Freire T, Malgor R, Medeiros A, Osinaga E, Carmona C. Mucin-type O-glycosylation in helminth parasites from major taxonomic groups: evidence for widespread distribution of the Tn antigen (GalNAc-Ser/Thr) and identification of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase activity. J Parasitol. 2003;89:709–14.
Article
CAS
PubMed
Google Scholar
Ubillos L, Medeiros A, Cancela M, Casaravilla C, Saldaña J, Domínguez L, et al. Characterization of the carcinoma-associated Tk antigen in helminth parasites. Exp Parasitol. 2007;116:129–36.
Article
CAS
PubMed
Google Scholar
Seledtsova GV, Shishkov AA, Kaschenko EA, Seledtsov VI. Xenogeneic cell-based vaccine therapy for colorectal cancer: safety, association of clinical effects with vaccine-induced immune responses. Biomed Pharmacother. 2016;83:1247–52.
Article
CAS
PubMed
Google Scholar
Wang ZQ, Liu RD, Sun GG, Song YY, Jiang P, Zhang X, et al. Proteomic analysis of Trichinella spiralis adult worm excretory-secretory proteins recognized by sera of patients with early trichinellosis. Front Microbiol. 2017;8:986.
Article
PubMed
PubMed Central
Google Scholar
Ren HN, Guo KX, Zhang Y, Sun GG, Liu RD, Jiang P, et al. Molecular characterization of a 31 kDa protein from Trichinella spiralis and its induced immune protection in BALB/c mice. Parasit Vectors. 2018;11:625.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wang XL, Liu MY, Sun SM, Liu XL, Yu L, Wang XR, et al. An anti-tumor protein produced by Trichinella spiralis induces apoptosis in human hepatoma H7402 cells. Vet Parasitol. 2013;194:186–8.
Article
CAS
PubMed
Google Scholar
Weatherly NF. Increased survival of Swiss mice given sublethal infections of Trichinella spiralis. J Parasitol. 1970;56:748–52.
Article
CAS
PubMed
Google Scholar
Molinari JA, Ebersole JL. Antineoplastic effects of long-term Trichinella spiralis infection on B-16 melanoma. Int Arch Allergy Appl Immunol. 1977;55:444–8.
Article
CAS
PubMed
Google Scholar
Kang YJ, Jo JO, Cho MK, Yu HS, Leem SH, Song KS, et al. Trichinella spiralis infection reduces tumor growth and metastasis of B16–F10 melanoma cells. Vet Parasitol. 2013;196:106–13.
Article
CAS
PubMed
Google Scholar
Wang XL, Fu BQ, Yang SJ, Wu XP, Cui GZ, Liu MF, et al. Trichinella spiralis–a potential anti-tumor agent. Vet Parasitol. 2009;159:249–52.
Article
CAS
PubMed
Google Scholar
Luo J, Yu L, Xie G, Li D, Su M, Zhao X, et al. Study on the mitochondrial apoptosis pathways of small cell lung cancer H446 cells induced by Trichinella spiralis muscle larvae ESPs. Parasitology. 2017;144:793–800.
Article
CAS
PubMed
Google Scholar
Wu H, Li M, Shao X, An Z, Du J, Yin H, et al. Trichinella spiralis muscle larvae excretory/secretory products trigger apoptosis and s-phase arrest of the non-small-cell lung cancer line A549. Exp Parasitol. 2020;218:107983.
Article
CAS
PubMed
Google Scholar
Gong P, Zhang J, Cao L, Nan Z, Li J, Yang J, et al. Identification and characterization of myeloma-associated antigens in Trichinella spiralis. Exp Parasitol. 2011;127:784–8.
Article
CAS
PubMed
Google Scholar
Duan L, Li J, Cheng B, Lv Q, Gong PT, Su LB, et al. Identification of a novel gene product expressed by Trichinella spiralis that binds antiserum to Sp2/0 myeloma cells. Vet Parasitol. 2013;194:183–5.
Article
CAS
PubMed
Google Scholar
Bramwell VH. Osteosarcomas and other cancers of bone. Curr Opin Oncol. 2000;12:330–6.
Article
CAS
PubMed
Google Scholar
Wu K, Türk TR, Rauen U, Su S, Feldkamp T, de Groot H, et al. Prolonged cold storage using a new histidine-tryptophan-ketoglutarate-based preservation solution in isogeneic cardiac mouse grafts. Eur Heart J. 2011;32:509–16.
Article
CAS
PubMed
Google Scholar
Camargo CA Jr, Madden JF, Gao W, Selvan RS, Clavien PA. Interleukin-6 protects liver against warm ischemia/reperfusion injury and promotes hepatocyte proliferation in the rodent. Hepatology. 1997;26:1513–20.
Article
CAS
PubMed
Google Scholar
Schwab L, Goroncy L, Palaniyandi S, Gautam S, Triantafyllopoulou A, Mocsai A, et al. Neutrophil granulocytes recruited upon translocation of intestinal bacteria enhance graft-versus-host disease via tissue damage. Nat Med. 2014;20:648–54.
Article
CAS
PubMed
Google Scholar
Kredel M, Muellenbach RM, Schlegel N, Wunder C, Klingelhöfer M, Lange M, et al. Pulmonary effects of positive end-expiratory pressure and fluid therapy in experimental lung injury. Exp Lung Res. 2011;37:35–43.
Article
PubMed
Google Scholar
Jha RK, Yong MQ, Chen SH. The protective effect of resveratrol on the intestinal mucosal barrier in rats with severe acute pancreatitis. Med Sci Monit. 2008;14:Br14-9.
CAS
PubMed
Google Scholar
Vasilev S, Ilic N, Gruden-Movsesijan A, Vasilijic S, Bosic M, Sofronic-Milosavljevic L. Necrosis and apoptosis in Trichinella spiralis-mediated tumour reduction. Cent Eur J Immunol. 2015;40:42–53.
Article
PubMed
PubMed Central
Google Scholar
Liao C, Cheng X, Liu M, Wang X, Boireau P. Trichinella spiralis and tumors: cause, coincidence or treatment? Anticancer Agents Med Chem. 2018;18:1091–9.
Article
CAS
PubMed
PubMed Central
Google Scholar
Briggs N, Weatherhead J, Sastry KJ, Hotez PJ. The hygiene hypothesis and its inconvenient truths about helminth infections. PLoS Negl Trop Dis. 2016;10:e0004944.
Article
PubMed
PubMed Central
Google Scholar
Versini M, Jeandel PY, Bashi T, Bizzaro G, Blank M, Shoenfeld Y. Unraveling the hygiene hypothesis of helminthes and autoimmunity: origins, pathophysiology, and clinical applications. BMC Med. 2015;13:81.
Article
PubMed
PubMed Central
CAS
Google Scholar
Plati J, Bucur O, Khosravi-Far R. Apoptotic cell signaling in cancer progression and therapy. Integr Biol. 2011;3:279–96.
Article
CAS
Google Scholar
Pistritto G, Trisciuoglio D, Ceci C, Garufi A, D’Orazi G. Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies. Aging. 2016;8:603–19.
Article
CAS
PubMed
PubMed Central
Google Scholar
Balleine RL, Fejzo MS, Sathasivam P, Basset P, Clarke CL, Byrne JA. The hD52 (TPD52) gene is a candidate target gene for events resulting in increased 8q21 copy number in human breast carcinoma. Genes Chromosom Cancer. 2000;29:48–57.
Article
CAS
PubMed
Google Scholar
Payton LA, Lewis JD, Byrne JA, Bright RK. Vaccination with metastasis-related tumor associated antigen TPD52 and CpG/ODN induces protective tumor immunity. Cancer Immunol Immunother. 2008;57:799–811.
Article
CAS
PubMed
Google Scholar
Adamson B, Smogorzewska A, Sigoillot FD, King RW, Elledge SJ. A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response. Nat Cell Biol. 2012;14:318–28.
Article
CAS
PubMed
PubMed Central
Google Scholar
Messenger SW, Thomas DD, Falkowski MA, Byrne JA, Gorelick FS, Groblewski GE. Tumor protein D52 controls trafficking of an apical endolysosomal secretory pathway in pancreatic acinar cells. Am J Physiol Gastrointest Liver Physiol. 2013;305:G439–52.
Article
CAS
PubMed
PubMed Central
Google Scholar
Frizinsky S, Haj-Yahia S, Machnes Maayan D, Lifshitz Y, Maoz-Segal R, Offengenden I, et al. The innate immune perspective of autoimmune and autoinflammatory conditions. Rheumatology. 2019;58:vi1–8.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hollenbaugh JA, Dutton RW. IFN-gamma regulates donor CD8 T cell expansion, migration, and leads to apoptosis of cells of a solid tumor. J Immunol. 2006;177:3004–11.
Article
CAS
PubMed
Google Scholar
Seynhaeve AL, Hoving S, Schipper D, Vermeulen CE, de Wiel-Ambagtsheer G, van Tiel ST, et al. Tumor necrosis factor alpha mediates homogeneous distribution of liposomes in murine melanoma that contributes to a better tumor response. Cancer Res. 2007;67:9455–62.
Article
CAS
PubMed
Google Scholar
Simstein R, Burow M, Parker A, Weldon C, Beckman B. Apoptosis, chemoresistance, and breast cancer: insights from the MCF-7 cell model system. Exp Biol Med. 2003;228:995–1003.
Article
CAS
Google Scholar
Mumm JB, Emmerich J, Zhang X, Chan I, Wu L, Mauze S, et al. IL-10 elicits IFNγ-dependent tumor immune surveillance. Cancer Cell. 2011;20:781–96.
Article
CAS
PubMed
Google Scholar
Trinchieri G. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev Immunol. 2003;3:133–46.
Article
CAS
PubMed
Google Scholar
Del Vecchio M, Bajetta E, Canova S, Lotze MT, Wesa A, Parmiani G, et al. Interleukin-12: biological properties and clinical application. Clin Cancer Res. 2007;13:4677–85.
Article
PubMed
Google Scholar
Smith MR. Rituximab (monoclonal anti-CD20 antibody): mechanisms of action and resistance. Oncogene. 2003;22:7359–68.
Article
CAS
PubMed
Google Scholar
Cardarelli PM, Quinn M, Buckman D, Fang Y, Colcher D, King DJ, et al. Binding to CD20 by anti-B1 antibody or F(ab’)(2) is sufficient for induction of apoptosis in B-cell lines. Cancer Immunol Immunother. 2002;51:15–24.
Article
CAS
PubMed
Google Scholar
Kim N, Cho D, Kim H, Kim S, Cha YJ, Greulich H, et al. Colorectal adenocarcinoma-derived EGFR mutants are oncogenic and sensitive to EGFR-targeted monoclonal antibodies, cetuximab and panitumumab. Int J Cancer. 2020;146:2194–200.
Article
CAS
PubMed
Google Scholar
Liu X, Lukowski JK, Flinders C, Kim S, Georgiadis RA, Mumenthaler SM, et al. MALDI-MSI of immunotherapy: mapping the EGFR-targeting antibody cetuximab in 3D colon-cancer cell cultures. Anal Chem. 2018;90:14156–64.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kroschinsky F, Stölzel F, Von Bonin S, Beutel G, Kochanek M, Kiehl M, et al. New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management. Crit Care. 2017;21:89.
Article
PubMed
PubMed Central
Google Scholar
Bugelski PJ, Achuthanandam R, Capocasale RJ, Treacy G, Bouman-Thio E. Monoclonal antibody-induced cytokine-release syndrome. Expert Rev Clin Immunol. 2009;5:499–521.
Article
CAS
PubMed
Google Scholar
Vogrig A, Muñiz-Castrillo S, Joubert B, Picard G, Rogemond V, Marchal C, et al. Central nervous system complications associated with immune checkpoint inhibitors. J Neurol Neurosurg Psychiatry. 2020;91:772–8.
Article
PubMed
Google Scholar
Michot JM, Bigenwald C, Champiat S, Collins M, Carbonnel F, Postel-Vinay S, et al. Immune-related adverse events with immune checkpoint blockade: a comprehensive review. Eur J Cancer. 2016;54:139–48.
Article
CAS
PubMed
Google Scholar
Aichberger KJ, Herndlhofer S, Schernthaner GH, Schillinger M, Mitterbauer-Hohendanner G, Sillaber C, et al. Progressive peripheral arterial occlusive disease and other vascular events during nilotinib therapy in CML. Am J Hematol. 2011;86:533–9.
Article
CAS
PubMed
Google Scholar
Markvardsen LH, Sindrup SH, Christiansen I, Olsen NK, Jakobsen J, Andersen H. Subcutaneous immunoglobulin as first-line therapy in treatment-naive patients with chronic inflammatory demyelinating polyneuropathy: randomized controlled trial study. Eur J Neurol. 2017;24:412–8.
Article
CAS
PubMed
Google Scholar