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Parasite genetics, genomics and proteomics

Subject Editor
Xing-Quan Zhu, Shanxi Agricultural University, China

Associate Editors
Stephen R. Doyle, Wellcome Sanger Institute, UK
Javier Sotillo-Gallego, National Centre for Microbiology, Spain
 

The Parasite genetics, genomics and proteomics section publishes studies applying platform technologies to the innovation of diagnostics, therapeutics and vaccines for parasitic diseases.

  1. The tropical bed bug, Cimex hemipterus, is an important ectoparasite causing various health problems. This species is mainly confined to tropical regions; however, insecticide resistance, global warming, and glob...

    Authors: Mohammad Bagher Ghavami, Zarafat Ghahremani, Narges Raeisi and Behrooz Taghiloo

    Citation: Parasites & Vectors 2021 14:470

    Content type: Research

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  2. Babesiosis is a tick-borne disease with global impact caused by parasites of the phylum Apicomplexa, genus Babesia. Typically, acute bovine babesiosis (BB) is characterized by fever, anemia, hemoglobinuria, and h...

    Authors: Lan He, Reginaldo G. Bastos, Yali Sun, Guohua Hua, Guiquan Guan, Junlong Zhao and Carlos E. Suarez

    Citation: Parasites & Vectors 2021 14:460

    Content type: Review

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  3. Head louse females secrete liquid glue during oviposition, which is solidified to form the nit sheath over the egg. Recently, two homologous proteins, named louse nit sheath protein (LNSP) 1 and LNSP 2, were i...

    Authors: Ju Hyeon Kim, Do Eun Lee, SangYoun Park, John M. Clark and Si Hyeock Lee

    Citation: Parasites & Vectors 2021 14:425

    Content type: Research

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  4. Leishmaniasis is a neglected tropical disease caused by several species of Leishmania. The resistance phenotype of these parasites depends on the characteristics of each species, which contributes to increased th...

    Authors: Julián Medina, Lissa Cruz-Saavedra, Luz Helena Patiño, Marina Muñoz and Juan David Ramírez

    Citation: Parasites & Vectors 2021 14:419

    Content type: Research

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  5. Toxoplasmosis caused by Toxoplasma gondii is a serious disease threatening human and animal health. People can be infected with T. gondii by ingesting raw pork contaminated with cysts or oocysts. Serological test...

    Authors: Yongle Song, Yongjuan Zhao, Ke Pan, Bang Shen, Rui Fang, Min Hu, Junlong Zhao and Yanqin Zhou

    Citation: Parasites & Vectors 2021 14:408

    Content type: Research

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  6. Epidemiological surveys in Oman have revealed a high prevalence of the co-occurrence of the pathogenic Theileria lestoquardi and the non-pathogenic Theileria ovis among sheep in the Barka region, Oman. Our most r...

    Authors: Salama Al-Hamidhi, Elshafie I. Elshafie, Saeed Yaghfoori, W. Ivan Morrison, Eugene H. Johnson and Hamza A. Babiker

    Citation: Parasites & Vectors 2021 14:370

    Content type: Research

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  7. Different genotypes of Echinococcus granulosus sensu stricto (s.s.) isolated from livestock and humans have been identified based on cox1 and nad1 genomic fragments. The present study was performed to differentia...

    Authors: Saeed Shahabi, Bahador Sarkari and Afshin Barazesh

    Citation: Parasites & Vectors 2021 14:369

    Content type: Short report

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  8. Superoxide dismutase (SOD), a central component of the antioxidant defence system of most organisms, removes excess superoxide anions by converting them to oxygen and hydrogen peroxide. As iron (Fe) SOD is abs...

    Authors: Ana Maria Murta Santi, Paula Alves Silva, Isabella Fernandes Martins Santos and Silvane Maria Fonseca Murta

    Citation: Parasites & Vectors 2021 14:366

    Content type: Short report

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  9. Pseudocohnilembus persalinus and Uronema marinum (Ciliophora, Scuticociliatia), as parasitic scuticociliatid ciliates, were isolated from Scophthalmus maximus and Takifugu rubripes, respectively, in our previous ...

    Authors: Yu-Xi Huang, Sen Wang, Yan-Qi Gao, Jie-Hu Chen, Xiu-Li Wang and Rui-Jun Li

    Citation: Parasites & Vectors 2021 14:318

    Content type: Research

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  10. Coccidiosis caused by Eimeria stiedae is a widespread and economically significant disease of rabbits. The lack of studies on the life-cycle development and host interactions of E. stiedae at the molecular level ...

    Authors: Yue Xie, Jie Xiao, Xuan Zhou, Xiaobin Gu, Ran He, Jing Xu, Bo Jing, Xuerong Peng and Guangyou Yang

    Citation: Parasites & Vectors 2021 14:308

    Content type: Research

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  11. Cystic echinococcosis (CE) is a parasitic disease that is caused by Echinococcus granulosus (Eg). The recombinant Echinococcus granulosus antigen P29 (rEg.P29) was shown to confer effective immunity to sheep and ...

    Authors: Chan Wang, Song-Hao Yang, Nan Niu, Jia Tao, Xian-Cai Du, Ji-Hui Yang, Ming-Xing Zhu, Ya-Na Wang and Wei Zhao

    Citation: Parasites & Vectors 2021 14:295

    Content type: Research

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  12. Panstrongylus megistus is the most important vector of Chagas disease in Brazil. Studies show that the principal factor hindering the control of triatomines is reinfestation of houses previously treated with inse...

    Authors: Flávio Campos Ferreira, Leilane Oliveira Gonçalves, Jeronimo Conceição Ruiz, Leonardo Barbosa Koerich, Fabiano Sviatopolk Mirsky Pais, Lileia Gonçalves Diotaiuti and Carlota Josefovicz Belisário

    Citation: Parasites & Vectors 2021 14:273

    Content type: Short report

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  13. Fragmented mitochondrial (mt) genomes and extensive mt gene rearrangements have been frequently reported from parasitic lice (Insecta: Phthiraptera). However, relatively little is known about the mt genomes fr...

    Authors: Yu Nie, Yi-Tian Fu, Yu Zhang, Yuan-Ping Deng, Wei Wang, Ya Tu and Guo-Hua Liu

    Citation: Parasites & Vectors 2021 14:269

    Content type: Research

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  14. The predominant genotype of Toxoplasma in China is the Chinese 1 (ToxoDB#9) lineage. TgCtwh3 and TgCtwh6 are two representative strains of Chinese 1, exhibiting high and low virulence to mice, respectively. Littl...

    Authors: Yang Wang, Chengjian Han, Rongsheng zhou, Jinjin Zhu, Famin Zhang, Jingyang Li, Qingli Luo, Jian Du, Deyong Chu, Yihong Cai, Jilong Shen and Li Yu

    Citation: Parasites & Vectors 2021 14:253

    Content type: Research

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  15. Schistosoma japonicum is a parasitic flatworm that is the aetiological agent of human schistosomiasis, an important cause of hepatic fibrosis. Schistosomiasis-induced hepatic fibrosis is a consequence of the high...

    Authors: Jing Huang, Xinguang Yin, Lifang Zhang, Ming Yao, Dahai Wei and Yiming Wu

    Citation: Parasites & Vectors 2021 14:232

    Content type: Research

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  16. The mitochondrial (mt) genomes of Sarcoptiformes mites typically contain 37 genes. Although the loss of genes is rare in Sarcoptiformes mite mitogenomes, two of the six previously reported oribatid mites (Acar...

    Authors: Xue-Bing Zhan, Bing Chen, Yu Fang, Fang-Yuan Dong, Wei-Xi Fang, Qian Luo, Ling-Miao Chu, Rui Feng, Yan Wang, Xuan Su, Ying Fang, Jiao-Yang Xu, Ze-Tao Zuo, Xing-Quan Xia, Jie-Gen Yu and En-Tao Sun

    Citation: Parasites & Vectors 2021 14:221

    Content type: Research

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  17. Biliary tract infection with the carcinogenic human liver fluke, Clonorchis sinensis, provokes chronic inflammation, epithelial hyperplasia, periductal fibrosis, and even cholangiocarcinoma. Complications are pro...

    Authors: Jung-Woong Kim, Junyeong Yi, Jinhong Park, Ji Hoon Jeong, Jinho Kim, Jihee Won, Seok Chung, Tong-Soo Kim and Jhang Ho Pak

    Citation: Parasites & Vectors 2021 14:213

    Content type: Research

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  18. Nematodes of the family Cosmocercidae (Ascaridomorpha: Cosmocercoidea) are mainly parasitic in the digestive tract of various amphibians and reptiles worldwide. However, our knowledge of the molecular phylogen...

    Authors: Hui-Xia Chen, Xiao-Hong Gu, Xue-Feng Ni and Liang Li

    Citation: Parasites & Vectors 2021 14:165

    Content type: Research

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  19. Entamoeba species harbored by humans have different degrees of pathogenicity. The present study explores the intra- and interspecific diversity, phylogenetic relationships, prevalence and distribution of tetra- a...

    Authors: Deiviane Aparecida Calegar, Kerla Joeline Lima Monteiro, Polyanna Araújo Alves Bacelar, Brenda Bulsara Costa Evangelista, Mayron Morais Almeida, Jéssica Pereira dos Santos, Márcio Neves Boia, Beatriz Coronato-Nunes, Lauren Hubert Jaeger and Filipe Anibal Carvalho-Costa

    Citation: Parasites & Vectors 2021 14:160

    Content type: Research

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  20. The NF-κB signalling pathway has been reported to be related to liver fibrosis, and we investigated whether the NF-κB signalling pathway is involved in liver fibrosis caused by secreted phospholipase A2 of Clonor...

    Authors: Yin-Juan Wu, Qing He, Mei Shang, Ying-Xuan Yin, Ye Li, Xue Du and Xue-Rong Li

    Citation: Parasites & Vectors 2021 14:152

    Content type: Research

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  21. Parasites of the genus Trichinella are the pathogenic agents of trichinellosis, which is a widespread and severe foodborne parasitic disease. Trichinella spiralis resides primarily in mammalian skeletal muscle ce...

    Authors: Xiaoxiang Hu, Xiaolei Liu, Chen Li, Yulu Zhang, Chengyao Li, Yanfeng Li, Yingxi Chen, Heng Guo, Xue Bai and Mingyuan Liu

    Citation: Parasites & Vectors 2021 14:130

    Content type: Research

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  22. Excretory-secretory (ES) products are crucial in maintaining helminths in the host. Consequently, the proteins of ES are potential vaccine molecules and potential therapeutic agents for autoimmune diseases. Helig...

    Authors: Marta Maruszewska-Cheruiyot, Ludmiła Szewczak, Katarzyna Krawczak-Wójcik, Magdalena Głaczyńska and Katarzyna Donskow-Łysoniewska

    Citation: Parasites & Vectors 2021 14:106

    Content type: Research

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  23. Cystic echinococcosis is a parasitic zoonotic disease, which poses a threat to public health and animal husbandry, and causes significant economic losses. Annexins are a family of phospholipid-binding proteins...

    Authors: Hongyu Song, Xue He, Xiaodi Du, Ruiqi Hua, Jing Xu, Ran He, Yue Xie, Xiaobin Gu, Xuerong Peng and Guangyou Yang

    Citation: Parasites & Vectors 2021 14:103

    Content type: Research

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  24. Culicoides imicola (Diptera: Ceratopogonidae) is an important Afrotropical and Palearctic vector of disease, transmitting viruses of animal health and economic significance including African horse sickness and bl...

    Authors: Jack Pilgrim, Stefanos Siozios, Matthew Baylis, Gert Venter, Claire Garros and Gregory D. D. Hurst

    Citation: Parasites & Vectors 2021 14:100

    Content type: Short report

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    The Correction to this article has been published in Parasites & Vectors 2021 14:128

  25. Small non-coding RNAs play critical regulatory roles in post-transcription. However, their characteristics in Trichomonas vaginalis, the causative agent of human sexually transmitted trichomoniasis, still remain ...

    Authors: Zhen-Sheng Wang, Hong-Chang Zhou, Chun-Yan Wei, Zhi-Hua Wang, Xiao Hao, Lian-Hui Zhang, Jing-Zhong Li, Zeng-Lei Wang and Heng Wang

    Citation: Parasites & Vectors 2021 14:87

    Content type: Research

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  26. Cryptosporidiosis is a gastrointestinal disease with global distribution. It has been a reportable disease in Canada since 2000; however, routine molecular surveillance is not conducted. Therefore, sources of ...

    Authors: Rebecca A. Guy, Christine A. Yanta, Pia K. Muchaal, Marisa A. Rankin, Karine Thivierge, Rachel Lau and Andrea K. Boggild

    Citation: Parasites & Vectors 2021 14:69

    Content type: Research

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  27. Babesia is a protozoan parasite that infects red blood cells in some vertebrates. Some species of Babesia can induce zoonoses and cause considerable harm. As the largest immune organ in mammals, the spleen plays ...

    Authors: Xiaomin Xue, Shuguang Ren, Xiaohong Yang, Abolfazl Masoudi, Yuhong Hu, Xiaoshuang Wang, Hongxia Li, Xiaojing Zhang, Minjing Wang, Hui Wang and Jingze Liu

    Citation: Parasites & Vectors 2021 14:61

    Content type: Research

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  28. The avian haematophagous ectoparasite Dermanyssus gallinae, commonly known as the poultry red mite, causes significant economic losses to the egg-laying industry worldwide and also represents a significant welfar...

    Authors: Wan Chen, Kathryn Bartley, Francesca Nunn, Alan S. Bowman, Jeremy M. Sternberg, Stewart T. G. Burgess, Alasdair J. Nisbet and Daniel R. G. Price

    Citation: Parasites & Vectors 2021 14:57

    Content type: Research

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  29. Blastocystis sp. is an anaerobic protozoan that parasitizes many animal hosts and the human gastrointestinal tract, and its pathogenicity is controversial. Captive wildlife may be potential reservoirs for human i...

    Authors: Lei Deng, Jingxin Yao, Shanyu Chen, Tingmei He, Yijun Chai, Ziyao Zhou, Xiaogang Shi, Haifeng Liu, Zhijun Zhong, Hualin Fu and Guangneng Peng

    Citation: Parasites & Vectors 2021 14:11

    Content type: Research

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  30. Eosinophilic meningitis, caused by fifth-stage larvae of the nematode (roundworm) Angiostrongylus cantonensis, is mainly attributed to the contribution of eosinophils to tissue inflammatory responses in helminthi...

    Authors: Wei-Wei Sun, Xiu-Mei Yan, Qing Shi, Yuan-Jiao Zhang, Jun-Ting Huang, Hui-Cong Huang, Hong-Fei Shi and Bao-Long Yan

    Citation: Parasites & Vectors 2020 13:617

    Content type: Research

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  31. Parasitic infections can increase susceptibility to bacterial co-infections. This may be true for urogenital schistosomiasis and bacterial urinary tract co-infections (UTI). We previously reported that this co...

    Authors: Evaristus C. Mbanefo, Loc Le, Luke F. Pennington, Yi- Ju Hsieh, Justin I. Odegaard, Kristina Lapira, Theodore S. Jardetzky, Franco H. Falcone and Michael H. Hsieh

    Citation: Parasites & Vectors 2020 13:615

    Content type: Research

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  32. Current measures for the prevention of dirofilariasis, caused by the dog heartworm, Dirofilaria immitis, rely on macrocyclic lactones, but evidence of drug-resistant isolates has called for alternative approaches...

    Authors: Tsai-Chi Shang Kuan and Roger K. Prichard

    Citation: Parasites & Vectors 2020 13:614

    Content type: Research

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  33. Schistosomiasis is a chronic, debilitating infectious disease caused by members of the genus Schistosoma. Previous findings have suggested a relationship between infection with Schistosoma spp. and alterations in...

    Authors: Tianqi Xia, Bikash Ranjan Giri, Jingyi Liu, Pengfei Du, Xue Li, Xuxin Li, Shun Li and Guofeng Cheng

    Citation: Parasites & Vectors 2020 13:601

    Content type: Research

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  34. One of the major challenges to leishmaniasis treatment is the emergence of parasites resistant to antimony. To study differentially expressed genes associated with drug resistance, we performed a comparative t...

    Authors: Juvana Moreira Andrade, Leilane Oliveira Gonçalves, Daniel Barbosa Liarte, Davi Alvarenga Lima, Frederico Gonçalves Guimarães, Daniela de Melo Resende, Ana Maria Murta Santi, Luciana Marcia de Oliveira, João Paulo Linhares Velloso, Renato Guimarães Delfino, Pascale Pescher, Gerald F. Späth, Jeronimo Conceição Ruiz and Silvane Maria Fonseca Murta

    Citation: Parasites & Vectors 2020 13:600

    Content type: Research

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  35. Larvae of the Australian sheep blowfly, Lucilia cuprina, parasitise sheep by feeding on skin excretions, dermal tissue and blood, causing severe damage known as flystrike or myiasis. Recent advances in -omic tech...

    Authors: Yair D. J. Prawer, Andreas J. Stroehlein, Neil D. Young, Shilpa Kapoor, Ross S. Hall, Razi Ghazali, Phillip Batterham, Robin B. Gasser, Trent Perry and Clare A. Anstead

    Citation: Parasites & Vectors 2020 13:598

    Content type: Research

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  36. Blastocystis sp. is one of the most common enteric parasites of humans and animals worldwide. It is well recognized that this ubiquitous protist displays a remarkable degree of genetic diversity in the SSU rRNA g...

    Authors: Jenny G. Maloney, Aleksey Molokin and Monica Santin

    Citation: Parasites & Vectors 2020 13:595

    Content type: Research

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  37. Cystic or alveolar echinococcosis caused by the larval stages of Echinococcus spp. is a very severe zoonotic helminth infection. Echinococcus shiquicus is a newly discovered species that has only been reported in...

    Authors: Guo-Qiang Zhu, Hong-Bin Yan, Li Li, John Asekhaen Ohiolei, Yan-Tao Wu, Wen-Hui Li, Nian-Zhang Zhang, Bao-Quan Fu and Wan-Zhong Jia

    Citation: Parasites & Vectors 2020 13:590

    Content type: Research

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  38. The ixodid tick Dermacentor marginatus is a vector of many pathogens wide spread in Eurasia. Studies of gene sequence on many tick species have greatly increased the information on tick protective antigen which m...

    Authors: Ercha Hu, Yuan Meng, Ying Ma, Ruiqi Song, Zhengxiang Hu, Min Li, Yunwei Hao, Xinli Fan, Liting Wei, Shilong Fan, Songqin Chen, Xuejie Zhai, Yongchang Li, Wei Zhang, Yang Zhang, Qingyong Guo…

    Citation: Parasites & Vectors 2020 13:563

    Content type: Research

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  39. Giardia duodenalis is one of the most prevalent and highly diverse human parasites, encompassing a complex of eight genetically distinct assemblages, each further divided into sub-assemblages. While in recent yea...

    Authors: Carmen Costache, Zsuzsa Kalmár, Horațiu Alexandru Colosi, Alina Mihaela Baciu, Răzvan Vlad Opriş, Adriana Györke and Ioana Alina Colosi

    Citation: Parasites & Vectors 2020 13:387

    Content type: Research

    Published on:

    The Correction to this article has been published in Parasites & Vectors 2021 14:325