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Helminths and helminthic diseases

Subject Editor
Martin Walker, Royal Veterinary College and Imperial College London, UK

Associate Editors

Martha Betson, University of Surrey, UK
Carlos Graeff Teixeira, Federal University of Espirito Santo, Brazil
Poppy Lamberton, University of Glasgow, UK
Scott Lawton, Scotland's Rural College, UK
Joaquin Prada, University of Surrey, UK
 

The Helminths and helminthic disease section publishes articles relating to parasitic Platyhelminthes, Nematoda and Acanthocephala including host-parasite relationships, epidemiology and disease, molecular taxonomy and phylogenetics, life-cycles and intermediate hosts, population genetics and community ecology.

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  1. Baylisascaris procyonis is a nematode parasite of the raccoon (Procyon lotor), and it can be responsible for a severe form of larva migrans in humans. This parasite has been reported from many countries all over ...

    Authors: Andrea Lombardo, Giuseppina Brocherel, Carla Donnini, Gianluca Fichi, Alessia Mariacher, Elena Lavinia Diaconu, Virginia Carfora, Antonio Battisti, Nadia Cappai, Luca Mattioli and Claudio De Liberato

    Citation: Parasites & Vectors 2022 15:24

    Content type: Short report

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  2. Despite the limited knowledge regarding the effects of deworming medication (DM) on nutritional indicators in sub-Saharan Africa (SSA), deworming programmes continue to be implemented in resource-limited count...

    Authors: Andy Bauleni, Fentanesh N. Tiruneh, Tisungane E. Mwenyenkulu, Owen Nkoka, Gowokani C. Chirwa, Steve Gowelo, Michael G. Chipeta and Peter A. M. Ntenda

    Citation: Parasites & Vectors 2022 15:7

    Content type: Research

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  3. There is ample evidence demonstrating a reverse relationship between helminth infection and immune-mediated diseases. Accordingly, several studies have shown that Echinococcus granulosus infection and hydatid cys...

    Authors: Sara Ghabdian, Sima Parande Shirvan, Mohsen Maleki and Hassan Borji

    Citation: Parasites & Vectors 2022 15:16

    Content type: Research

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  4. Annual mass drug administration with praziquantel has reduced schistosomiasis transmission in some highly endemic areas, but areas with persistent high endemicity have been identified across sub-Saharan Africa...

    Authors: Suzan C. M. Trienekens, Christina L. Faust, Fred Besigye, Lucy Pickering, Edridah M. Tukahebwa, Janet Seeley and Poppy H. L. Lamberton

    Citation: Parasites & Vectors 2022 15:15

    Content type: Research

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  5. Gastrointestinal nematodes are ubiquitous for both domestic and wild ungulates and have varying consequences for health and fitness. They exist as complex communities of multiple co-infecting species, and we h...

    Authors: Camille Beaumelle, Elizabeth M. Redman, Jill de Rijke, Janneke Wit, Slimania Benabed, François Debias, Jeanne Duhayer, Sylvia Pardonnet, Marie-Thérèse Poirel, Gilles Capron, Stéphane Chabot, Benjamin Rey, Glenn Yannic, John S. Gilleard and Gilles Bourgoin

    Citation: Parasites & Vectors 2021 14:594

    Content type: Research

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  6. Echinococcus multilocularis is the causative agent of human hepatic alveolar echinococcosis (AE). AE can cause damage to several organs, primarily the liver, and have severe outcomes, such as hepatic failure and ...

    Authors: Deping Cao, Emad Shamsan, Bofan Jiang, Haining Fan, Yaogang Zhang and Mustafa Abdo Saif Dehwah

    Citation: Parasites & Vectors 2021 14:593

    Content type: Research

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  7. Cysticercosis is a zoonotic neglected tropical disease (NTD) that affects humans and pigs following the ingestion of Taenia solium eggs. Human cysticercosis poses a substantial public health burden in endemic cou...

    Authors: Erika Galipó, Matthew A. Dixon, Claudio Fronterrè, Zulma M. Cucunubá, Maria-Gloria Basáñez, Kim Stevens, Astrid Carolina Flórez Sánchez and Martin Walker

    Citation: Parasites & Vectors 2021 14:590

    Content type: Research

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  8. Nematodes are presumably the most abundant Metazoa on Earth, and can even be found in some of the most hostile environments of our planet. Various types of hypobiosis evolved to adapt their life cycles to such...

    Authors: Lieke E. Vlaar, Andre Bertran, Mehran Rahimi, Lemeng Dong, Jan E. Kammenga, Johannes Helder, Aska Goverse and Harro J. Bouwmeester

    Citation: Parasites & Vectors 2021 14:554

    Content type: Review

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  9. Despite high black fly densities in persisting onchocerciasis foci in Cameroon, no vector control has ever been carried out to complement Community-Directed Treatment with Ivermectin (CDTI). As a prelude to co...

    Authors: André Domche, Hugues C. Nana-Djeunga, Linda Djune Yemeli, Cédric Lenou Nanga, Michel Boussinesq, Flobert Njiokou, Sébastien Pion and Joseph Kamgno

    Citation: Parasites & Vectors 2021 14:546

    Content type: Research

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  10. Necator americanus is one of the major etiological agents of human ancylostomiasis. Historically, the epidemiology of ancylostomiasis in Henan Province of central China and the molecular characteristics of N. ame...

    Authors: Fang Fang Xu, Yu Fei Niu, Wen Qing Chen, Sha Sha Liu, Jing Ru Li, Peng Jiang, Zhong Quan Wang, Jing Cui and Xi Zhang

    Citation: Parasites & Vectors 2021 14:537

    Content type: Short report

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  11. Intestinal parasites (IPs) are widely distributed worldwide and are one of the major contributors to gastrointestinal disease. Their prevalence is associated with poor access to water, sanitation and hygiene (...

    Authors: Ernesto Candela, Carolina Goizueta, M. Victoria Periago and Carla Muñoz-Antoli

    Citation: Parasites & Vectors 2021 14:510

    Content type: Research

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  12. There is an urgent need for an extensive evaluation of benzimidazole efficacy in humans. In veterinary science, benzimidazole resistance has been mainly associated with three single-nucleotide polymorphisms (S...

    Authors: Javier Gandasegui, Berta Grau-Pujol, María Cambra-Pelleja, Valdemiro Escola, Maria Antonietta Demontis, Anelsio Cossa, José Carlos Jamine, Rafael Balaña-Fouce, Lisette van Lieshout, José Muñoz and María Martínez-Valladares

    Citation: Parasites & Vectors 2021 14:490

    Content type: Research

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  13. The present clinical field trial was conducted to assess the efficacy of a broad-spectrum parasiticide spot-on formulation containing eprinomectin (Broadline®) against Thelazia callipaeda eyeworm in naturally inf...

    Authors: Stefania Zanet, Simone Morelli, Angela Di Cesare, Stefano Bò, Donato Traversa, Wilfried Lebon, Frederic Beugnet, Giulia Simonato and Ezio Ferroglio

    Citation: Parasites & Vectors 2021 14:477

    Content type: Research

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  14. Various stimuli, including Clonorchis sinensis infection, can cause liver fibrosis. Liver fibrosis is characterized by the activation of hepatic stellate cells (HSCs) with massive production of extracellular matr...

    Authors: Qian-Yang Zhou, Hui-Min Yang, Ji-Xin Liu, Na Xu, Jing Li, Li-Ping Shen, Yu-Zhao Zhang, Stephane Koda, Bei-Bei Zhang, Qian Yu, Jia-Xu Chen, Kui-Yang Zheng and Chao Yan

    Citation: Parasites & Vectors 2021 14:472

    Content type: Research

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  15. Harnessing helminth-based immunoregulation is a novel therapeutic strategy for many immune dysfunction disorders, including inflammatory bowel diseases (IBDs). We previously identified a small molecule peptide...

    Authors: Wenqi Shan, Wenzhe Zhang, Fei Xue, Yongbin Ma, Liyang Dong, Ting Wang, Yu Zheng, Dingqi Feng, Ming Chang, Guoyue Yuan and Xuefeng Wang

    Citation: Parasites & Vectors 2021 14:455

    Content type: Research

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  16. Tapeworm infections are among the tropical neglected parasitic diseases endemically occurring in Ethiopia. This systematic review and meta-analysis aims at estimating the pooled prevalence and distribution of Tae...

    Authors: Nigus Abebe Shumuye, John Asekhaen Ohiolei, Mebrahtu Berhe Gebremedhin, Hong-Bin Yan, Li Li, Wen-Hui Li, Nian-Zhang Zhang, Bao-Quan Fu and Wan-Zhong Jia

    Citation: Parasites & Vectors 2021 14:447

    Content type: Review

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  17. Manipulative parasites are thought to liberate molecules in their external environment, acting as manipulation factors with biological functions implicated in their host’s physiological and behavioural alterat...

    Authors: Chloé Suzanne Berger, Jérôme Laroche, Halim Maaroufi, Hélène Martin, Kyung-Mee Moon, Christian R. Landry, Leonard J. Foster and Nadia Aubin-Horth

    Citation: Parasites & Vectors 2021 14:436

    Content type: Research

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  18. Anaplasma platys is a tick-borne bacterium which infects blood platelets of dogs, causing canine cyclic thrombocytopenia. The disease is distributed worldwide, particularly in the tropics and subtropics, but info...

    Authors: Abdelfattah Selim, Hamdan Almohammed, Abdelhamed Abdelhady, Abdulaziz Alouffi and Fahdah Ayed Alshammari

    Citation: Parasites & Vectors 2021 14:429

    Content type: Short report

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  19. Cystic echinococcosis (CE) is a worldwide parasitic zoonosis caused by the larval stage of Echinococcus granulosus sensu lato affecting livestock, particularly sheep and goats. However, often this parasitosis is ...

    Authors: Antonio Bosco, Leucio Camara Alves, Paola Cociancic, Alessandra Amadesi, Paola Pepe, Maria Elena Morgoglione, Maria Paola Maurelli, Edyniesky Ferrer-Miranda, Kleber Régis Santoro, Rafael Antonio Nascimento Ramos, Laura Rinaldi and Giuseppe Cringoli

    Citation: Parasites & Vectors 2021 14:421

    Content type: Research

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  20. The diagnosis of strongyloidiasis is challenging. Serological tests are acknowledged to have high sensitivity, but issues due to cross-reactions with other parasites, native parasite antigen supply and intrins...

    Authors: Francesca Tamarozzi, Silvia Stefania Longoni, Cristina Mazzi, Sofia Pettene, Antonio Montresor, Siddhartha Mahanty, Zeno Bisoffi and Dora Buonfrate

    Citation: Parasites & Vectors 2021 14:412

    Content type: Research

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  21. The tropical disease onchocerciasis (river blindness), caused by Onchocerca volvulus filarial nematodes, is targeted for elimination by mass treatment with nematocidal and antimicrobial drugs. Diagnosis of O. vol...

    Authors: Vera Wewer, Helga Peisker, Katharina Gutbrod, Mazen Al-Bahra, Dirk Menche, Ngongeh Glory Amambo, Fanny F. Fombad, Abdel Jelil Njouendou, Kenneth Pfarr, Samuel Wanji, Achim Hoerauf and Peter Dörmann

    Citation: Parasites & Vectors 2021 14:397

    Content type: Research

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  22. Schistosomiasis a neglected tropical disease  endemic in Brazil. It is caused by the trematode Schistosoma mansoni, which is transmitted by snails of the genus Biomphalaria. Among measures used to control and eli...

    Authors: Silvia Gonçalves Mesquita, Floria Gabriela dos Santos Neves, Ronaldo Guilherme Carvalho Scholte, Omar dos Santos Carvalho, Cristina Toscano Fonseca and Roberta Lima Caldeira

    Citation: Parasites & Vectors 2021 14:388

    Content type: Research

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  23. Angiostrongylus costaricensis is a zoonotic parasitic nematode described for the first time in 1971 by Pedro Morera and Rodolfo Céspedes in Costa Rica. This parasite causes an infection known as abdominal angiost...

    Authors: Alicia Rojas, Arnaldo Maldonado-Junior, Javier Mora, Alessandra Morassutti, Rubens Rodriguez, Alberto Solano-Barquero, Anamariela Tijerino, Marianela Vargas and Carlos Graeff-Teixeira

    Citation: Parasites & Vectors 2021 14:374

    Content type: Review

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  24. Freshwater fauna of the Middle East encompass elements shared with three continents—Africa, Asia, and Europe—and the Middle East is, therefore, considered a historical geographic crossroad between these three ...

    Authors: Michal Benovics, Farshad Nejat, Asghar Abdoli and Andrea Šimková

    Citation: Parasites & Vectors 2021 14:372

    Content type: Research

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  25. The cryopreservation of filarial nematodes has been studied for nearly 70 years. Largely, these studies examined the effectiveness of cryopreservation methods by using the post-thaw survival of microfilariae (...

    Authors: Erich W. Zinser, Tom L. McTier, Nicole S. Kernell and Debra J. Woods

    Citation: Parasites & Vectors 2021 14:367

    Content type: Research

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  26. Trichinella spiralis ranks seventh in the risk posed by foodborne parasites. It causes most human cases of trichinellosis and is the most frequent cause of Trichinella outbreaks on pig farms and in wild boar, wor...

    Authors: Ewa Bilska-Zajac, Daniele Tonanzi, Edoardo Pozio, Miroslaw Rozycki, Tomasz Cencek, Peter C. Thompson, Benjamin M. Rosenthal and Giuseppe La Rosa

    Citation: Parasites & Vectors 2021 14:359

    Content type: Research

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  27. Zoonotic diseases are a serious threat to both public health and animal conservation. Most non-human primates (NHP) are facing the threat of forest loss and fragmentation and are increasingly living in closer ...

    Authors: C. Sirima, C. Bizet, H. Hamou, B. Červená, T. Lemarcis, A. Esteban, M. Peeters, E. Mpoudi Ngole, I. M. Mombo, F. Liégeois, K. J. Petrželková, M. Boussinesq and S. Locatelli

    Citation: Parasites & Vectors 2021 14:354

    Content type: Research

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  28. Echinococcosis is a severe zoonotic parasitic disease which severely affects the health of the hosts. The diagnosis of echinococcosis depends mainly on imaging examination. However, the patient is often in the...

    Authors: Mingxing Zhu, Xiancai Du, Hongxia Xu, Songhao Yang, Chan Wang, Yazhou Zhu, Tingrui Zhang and Wei Zhao

    Citation: Parasites & Vectors 2021 14:324

    Content type: Research

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  29. The impact of semiannual mass drug administration (MDA) with albendazole (ALB; 400 mg) alone on lymphatic filariasis (LF) and soil-transmitted helminth (STH) infections was assessed during two trials conducted...

    Authors: Jérémy T. Campillo, Naomi P. Awaca-Uvon, Jean-Paul Tambwe, Godefroy Kuyangisa-Simuna, Johnny Vlaminck, Gary J. Weil, Michel Boussinesq, Cédric B. Chesnais and Sébastien D. S. Pion

    Citation: Parasites & Vectors 2021 14:310

    Content type: Research

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  30. Metastrongyloid parasites Angiostrongylus vasorum and Crenosoma vulpis infect wild and domestic canids and are important pathogens in dogs. Recent studies indicate that gastropod intermediate hosts infected with ...

    Authors: William Robbins, Gary Conboy, Spencer Greenwood and Roland Schaper

    Citation: Parasites & Vectors 2021 14:307

    Content type: Research

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  31. Drugs currently used for controlling onchocerciasis and lymphatic filariasis (LF) are mainly microfilaricidal, with minimal or no effect on the adult worms. For efficient management of these diseases, it is ne...

    Authors: Melanie Abongwa, Moses Samje, Godfred A. Ayimele, Smith B. Babiaka, Christina Bulman, Judy Sakanari, Nick J. Koszewski, Saurabh Verma, Jesse Goff, Fidelis Cho-Ngwa, Richard J. Martin and Alan P. Robertson

    Citation: Parasites & Vectors 2021 14:305

    Content type: Research

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  32. Plant-derived cysteine proteinases of the papain family (CPs) attack nematodes by digesting the cuticle, leading to rupture and death of the worm. The nematode cuticle is composed of collagens and cuticlins, b...

    Authors: Victor S. Njom, Tim Winks, Oumu Diallo, Ann Lowe, Jerzy Behnke, Mark J. Dickman, Ian Duce, Iain Johnstone and David J. Buttle

    Citation: Parasites & Vectors 2021 14:302

    Content type: Research

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  33. Trichinellosis is a foodborne disease caused by several Trichinella species around the world. In Chile, the domestic cycle was fairly well-studied in previous decades, but has been neglected in recent years. The ...

    Authors: Carlos Landaeta-Aqueveque, Salvador Ayala, Denis Poblete-Toledo and Mauricio Canals

    Citation: Parasites & Vectors 2021 14:282

    Content type: Short report

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  34. Hepatic stellate cell (HSC) activation plays a pivotal role in hepatic inflammation and liver fibrosis. TLR4 pathway activation has been reported to be involved in mice liver fibrosis induced by hepatitis viru...

    Authors: Lan Chen, Xiaofang Ji, Manni Wang, Xiaoyan Liao, Cuiying Liang, Juanjuan Tang, Zhencheng Wen, Ferrandon Dominique and Zi Li

    Citation: Parasites & Vectors 2021 14:279

    Content type: Research

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  35. The liver fluke Fasciola gigantica secretes excretory-secretory proteins during infection to mediate its interaction with the host. In this study, we investigated the immunomodulatory effects of a recombinant teg...

    Authors: Muhammad Ehsan, Rui-Si Hu, Jun-Ling Hou, Hany M. Elsheikha, Xiao-Dong Li, Pan-Hong Liang and Xing-Quan Zhu

    Citation: Parasites & Vectors 2021 14:276

    Content type: Research

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  36. The blood flukes of genus Schistosoma are the causative agent of schistosomiasis, a parasitic disease that infects more than 200 million people worldwide. Proteases of schistosomes are involved in critical steps ...

    Authors: Lenka Ulrychová, Pavel Ostašov, Marta Chanová, Michael Mareš, Martin Horn and Jan Dvořák

    Citation: Parasites & Vectors 2021 14:274

    Content type: Research

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  37. Cystic echinococcosis (CE) is a parasitic zoonosis caused by infection with the larval stage of Echinococcus granulosus (s.l.). This study investigated the prevalence and potential risk factors associated with hu...

    Authors: Leonardo Uchiumi, Guillermo Mujica, Daniel Araya, Juan Carlos Salvitti, Mariano Sobrino, Sergio Moguillansky, Alejandro Solari, Patricia Blanco, Fabiana Barrera, Janete Lamunier, Marcos Arezo, Marcos Seleiman, Zaida E. Yadon, Francesca Tamarozzi, Adriano Casulli and Edmundo Larrieu

    Citation: Parasites & Vectors 2021 14:262

    Content type: Research

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  38. Toxocariasis, caused by a nematode species of the genus Toxocara, has been described as one of the most prevalent zoonotic helminthiases worldwide. Human transmission may occur by ingesting Toxocara spp. larvae f...

    Authors: Paula Andreia Fabris Giudice, Susana Angélica Zevallos Lescano, William Henry Roldan Gonzáles, Rogério Giuffrida, Fernanda Nobre Bandeira, Louise Bach Kmetiuk, Andrea Pires dos Santos, Alexander Welker Biondo and Vamilton Alvares Santarém

    Citation: Parasites & Vectors 2021 14:250

    Content type: Research

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  39. Wolbachia is an obligate intracellular maternally transmitted, gram-negative bacterium which forms a spectrum of endosymbiotic relationships from parasitism to obligatory mutualism in a wide range of arthropods a...

    Authors: Ranju Ravindran Santhakumari Manoj, Maria Stefania Latrofa, Sara Epis and Domenico Otranto

    Citation: Parasites & Vectors 2021 14:245

    Content type: Review

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  40. Genetic markers are employed widely in molecular studies, and their utility depends on the degree of sequence variation, which dictates the type of application for which they are suited. Consequently, the suit...

    Authors: Abigail Hui En Chan, Kittipong Chaisiri, Sompob Saralamba, Serge Morand and Urusa Thaenkham

    Citation: Parasites & Vectors 2021 14:233

    Content type: Research

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  41. There are more than 300 species of capillariids that parasitize various vertebrate groups worldwide. Species identification is hindered because of the few taxonomically informative structures available, making...

    Authors: Victor Hugo Borba, Coralie Martin, José Roberto Machado-Silva, Samanta C. C. Xavier, Flávio L. de Mello and Alena Mayo Iñiguez

    Citation: Parasites & Vectors 2021 14:230

    Content type: Research

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  42. Dirofilariosis is a vector-borne parasitosis caused by filarial nematodes of the genus Dirofilaria. In humans, who represent accidental hosts, dirofilariosis is mostly caused by Dirofilaria repens and Dirofilaria...

    Authors: Katharina Riebenbauer, Philipp B. Weber, Julia Walochnik, Franz Karlhofer, Stefan Winkler, Sonja Dorfer, Herbert Auer, Julia Valencak, Martin Laimer and Alessandra Handisurya

    Citation: Parasites & Vectors 2021 14:227

    Content type: Research

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  43. The current studies compared ProHeart® 12, Heartgard® Plus and Interceptor® Plus for preventive efficacy against JYD-34, a macrocyclic lactone (ML)-resistant strain of Dirofilaria immitis in dogs.

    Authors: Tom L. McTier, Susan Holzmer, Kristina Kryda, Sean Mahabir, John W. McCall, Jami Trombley and Steven J. Maeder

    Citation: Parasites & Vectors 2021 14:226

    Content type: Research

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  44. Schistosomiasis is a chronic parasitic disease that affects millions of people’s health worldwide. Because of the increasing drug resistance to praziquantel (PZQ), which is the primary drug for schistosomiasis...

    Authors: Gongming Li, Qingqing Guo, Chao Feng, Huan Chen, Wenjiao Zhao, Shu Li, Yang Hong and Dequn Sun

    Citation: Parasites & Vectors 2021 14:225

    Content type: Research

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