Skip to main content

Helminths and helminthic diseases

Subject Editor
Martin Walker, Royal Veterinary College and Imperial College London, UK

Associate Editors
Carlos Graeff Teixeira, Federal University of Espirito Santo, Brazil
Poppy Lamberton, University of Glasgow, UK
Scott Lawton, Scotland's Rural College, UK
Joaquin Prada, University of Surrey, UK
 

The Helminths and helminthic disease section publishes articles relating to parasitic Platyhelminthes, Nematoda and Acanthocephala including host-parasite relationships, epidemiology and disease, molecular taxonomy and phylogenetics, life-cycles and intermediate hosts, population genetics and community ecology.

Page 1 of 2

  1. The present clinical field trial was conducted to assess the efficacy of a broad-spectrum parasiticide spot-on formulation containing eprinomectin (Broadline®) against Thelazia callipaeda eyeworm in naturally inf...

    Authors: Stefania Zanet, Simone Morelli, Angela Di Cesare, Stefano Bò, Donato Traversa, Wilfried Lebon, Frederic Beugnet, Giulia Simonato and Ezio Ferroglio

    Citation: Parasites & Vectors 2021 14:477

    Content type: Research

    Published on:

  2. Various stimuli, including Clonorchis sinensis infection, can cause liver fibrosis. Liver fibrosis is characterized by the activation of hepatic stellate cells (HSCs) with massive production of extracellular matr...

    Authors: Qian-Yang Zhou, Hui-Min Yang, Ji-Xin Liu, Na Xu, Jing Li, Li-Ping Shen, Yu-Zhao Zhang, Stephane Koda, Bei-Bei Zhang, Qian Yu, Jia-Xu Chen, Kui-Yang Zheng and Chao Yan

    Citation: Parasites & Vectors 2021 14:472

    Content type: Research

    Published on:

  3. Harnessing helminth-based immunoregulation is a novel therapeutic strategy for many immune dysfunction disorders, including inflammatory bowel diseases (IBDs). We previously identified a small molecule peptide...

    Authors: Wenqi Shan, Wenzhe Zhang, Fei Xue, Yongbin Ma, Liyang Dong, Ting Wang, Yu Zheng, Dingqi Feng, Ming Chang, Guoyue Yuan and Xuefeng Wang

    Citation: Parasites & Vectors 2021 14:455

    Content type: Research

    Published on:

  4. Tapeworm infections are among the tropical neglected parasitic diseases endemically occurring in Ethiopia. This systematic review and meta-analysis aims at estimating the pooled prevalence and distribution of Tae...

    Authors: Nigus Abebe Shumuye, John Asekhaen Ohiolei, Mebrahtu Berhe Gebremedhin, Hong-Bin Yan, Li Li, Wen-Hui Li, Nian-Zhang Zhang, Bao-Quan Fu and Wan-Zhong Jia

    Citation: Parasites & Vectors 2021 14:447

    Content type: Review

    Published on:

  5. Manipulative parasites are thought to liberate molecules in their external environment, acting as manipulation factors with biological functions implicated in their host’s physiological and behavioural alterat...

    Authors: Chloé Suzanne Berger, Jérôme Laroche, Halim Maaroufi, Hélène Martin, Kyung-Mee Moon, Christian R. Landry, Leonard J. Foster and Nadia Aubin-Horth

    Citation: Parasites & Vectors 2021 14:436

    Content type: Research

    Published on:

  6. Anaplasma platys is a tick-borne bacterium which infects blood platelets of dogs, causing canine cyclic thrombocytopenia. The disease is distributed worldwide, particularly in the tropics and subtropics, but info...

    Authors: Abdelfattah Selim, Hamdan Almohammed, Abdelhamed Abdelhady, Abdulaziz Alouffi and Fahdah Ayed Alshammari

    Citation: Parasites & Vectors 2021 14:429

    Content type: Short report

    Published on:

  7. Cystic echinococcosis (CE) is a worldwide parasitic zoonosis caused by the larval stage of Echinococcus granulosus sensu lato affecting livestock, particularly sheep and goats. However, often this parasitosis is ...

    Authors: Antonio Bosco, Leucio Camara Alves, Paola Cociancic, Alessandra Amadesi, Paola Pepe, Maria Elena Morgoglione, Maria Paola Maurelli, Edyniesky Ferrer-Miranda, Kleber Régis Santoro, Rafael Antonio Nascimento Ramos, Laura Rinaldi and Giuseppe Cringoli

    Citation: Parasites & Vectors 2021 14:421

    Content type: Research

    Published on:

  8. The diagnosis of strongyloidiasis is challenging. Serological tests are acknowledged to have high sensitivity, but issues due to cross-reactions with other parasites, native parasite antigen supply and intrins...

    Authors: Francesca Tamarozzi, Silvia Stefania Longoni, Cristina Mazzi, Sofia Pettene, Antonio Montresor, Siddhartha Mahanty, Zeno Bisoffi and Dora Buonfrate

    Citation: Parasites & Vectors 2021 14:412

    Content type: Research

    Published on:

  9. The tropical disease onchocerciasis (river blindness), caused by Onchocerca volvulus filarial nematodes, is targeted for elimination by mass treatment with nematocidal and antimicrobial drugs. Diagnosis of O. vol...

    Authors: Vera Wewer, Helga Peisker, Katharina Gutbrod, Mazen Al-Bahra, Dirk Menche, Ngongeh Glory Amambo, Fanny F. Fombad, Abdel Jelil Njouendou, Kenneth Pfarr, Samuel Wanji, Achim Hoerauf and Peter Dörmann

    Citation: Parasites & Vectors 2021 14:397

    Content type: Research

    Published on:

  10. Schistosomiasis a neglected tropical disease  endemic in Brazil. It is caused by the trematode Schistosoma mansoni, which is transmitted by snails of the genus Biomphalaria. Among measures used to control and eli...

    Authors: Silvia Gonçalves Mesquita, Floria Gabriela dos Santos Neves, Ronaldo Guilherme Carvalho Scholte, Omar dos Santos Carvalho, Cristina Toscano Fonseca and Roberta Lima Caldeira

    Citation: Parasites & Vectors 2021 14:388

    Content type: Research

    Published on:

  11. Angiostrongylus costaricensis is a zoonotic parasitic nematode described for the first time in 1971 by Pedro Morera and Rodolfo Céspedes in Costa Rica. This parasite causes an infection known as abdominal angiost...

    Authors: Alicia Rojas, Arnaldo Maldonado-Junior, Javier Mora, Alessandra Morassutti, Rubens Rodriguez, Alberto Solano-Barquero, Anamariela Tijerino, Marianela Vargas and Carlos Graeff-Teixeira

    Citation: Parasites & Vectors 2021 14:374

    Content type: Review

    Published on:

  12. Freshwater fauna of the Middle East encompass elements shared with three continents—Africa, Asia, and Europe—and the Middle East is, therefore, considered a historical geographic crossroad between these three ...

    Authors: Michal Benovics, Farshad Nejat, Asghar Abdoli and Andrea Šimková

    Citation: Parasites & Vectors 2021 14:372

    Content type: Research

    Published on:

  13. The cryopreservation of filarial nematodes has been studied for nearly 70 years. Largely, these studies examined the effectiveness of cryopreservation methods by using the post-thaw survival of microfilariae (...

    Authors: Erich W. Zinser, Tom L. McTier, Nicole S. Kernell and Debra J. Woods

    Citation: Parasites & Vectors 2021 14:367

    Content type: Research

    Published on:

  14. Trichinella spiralis ranks seventh in the risk posed by foodborne parasites. It causes most human cases of trichinellosis and is the most frequent cause of Trichinella outbreaks on pig farms and in wild boar, wor...

    Authors: Ewa Bilska-Zajac, Daniele Tonanzi, Edoardo Pozio, Miroslaw Rozycki, Tomasz Cencek, Peter C. Thompson, Benjamin M. Rosenthal and Giuseppe La Rosa

    Citation: Parasites & Vectors 2021 14:359

    Content type: Research

    Published on:

  15. Zoonotic diseases are a serious threat to both public health and animal conservation. Most non-human primates (NHP) are facing the threat of forest loss and fragmentation and are increasingly living in closer ...

    Authors: C. Sirima, C. Bizet, H. Hamou, B. Červená, T. Lemarcis, A. Esteban, M. Peeters, E. Mpoudi Ngole, I. M. Mombo, F. Liégeois, K. J. Petrželková, M. Boussinesq and S. Locatelli

    Citation: Parasites & Vectors 2021 14:354

    Content type: Research

    Published on:

  16. Echinococcosis is a severe zoonotic parasitic disease which severely affects the health of the hosts. The diagnosis of echinococcosis depends mainly on imaging examination. However, the patient is often in the...

    Authors: Mingxing Zhu, Xiancai Du, Hongxia Xu, Songhao Yang, Chan Wang, Yazhou Zhu, Tingrui Zhang and Wei Zhao

    Citation: Parasites & Vectors 2021 14:324

    Content type: Research

    Published on:

  17. The impact of semiannual mass drug administration (MDA) with albendazole (ALB; 400 mg) alone on lymphatic filariasis (LF) and soil-transmitted helminth (STH) infections was assessed during two trials conducted...

    Authors: Jérémy T. Campillo, Naomi P. Awaca-Uvon, Jean-Paul Tambwe, Godefroy Kuyangisa-Simuna, Johnny Vlaminck, Gary J. Weil, Michel Boussinesq, Cédric B. Chesnais and Sébastien D. S. Pion

    Citation: Parasites & Vectors 2021 14:310

    Content type: Research

    Published on:

  18. Metastrongyloid parasites Angiostrongylus vasorum and Crenosoma vulpis infect wild and domestic canids and are important pathogens in dogs. Recent studies indicate that gastropod intermediate hosts infected with ...

    Authors: William Robbins, Gary Conboy, Spencer Greenwood and Roland Schaper

    Citation: Parasites & Vectors 2021 14:307

    Content type: Research

    Published on:

  19. Drugs currently used for controlling onchocerciasis and lymphatic filariasis (LF) are mainly microfilaricidal, with minimal or no effect on the adult worms. For efficient management of these diseases, it is ne...

    Authors: Melanie Abongwa, Moses Samje, Godfred A. Ayimele, Smith B. Babiaka, Christina Bulman, Judy Sakanari, Nick J. Koszewski, Saurabh Verma, Jesse Goff, Fidelis Cho-Ngwa, Richard J. Martin and Alan P. Robertson

    Citation: Parasites & Vectors 2021 14:305

    Content type: Research

    Published on:

  20. Plant-derived cysteine proteinases of the papain family (CPs) attack nematodes by digesting the cuticle, leading to rupture and death of the worm. The nematode cuticle is composed of collagens and cuticlins, b...

    Authors: Victor S. Njom, Tim Winks, Oumu Diallo, Ann Lowe, Jerzy Behnke, Mark J. Dickman, Ian Duce, Iain Johnstone and David J. Buttle

    Citation: Parasites & Vectors 2021 14:302

    Content type: Research

    Published on:

  21. Trichinellosis is a foodborne disease caused by several Trichinella species around the world. In Chile, the domestic cycle was fairly well-studied in previous decades, but has been neglected in recent years. The ...

    Authors: Carlos Landaeta-Aqueveque, Salvador Ayala, Denis Poblete-Toledo and Mauricio Canals

    Citation: Parasites & Vectors 2021 14:282

    Content type: Short report

    Published on:

  22. Hepatic stellate cell (HSC) activation plays a pivotal role in hepatic inflammation and liver fibrosis. TLR4 pathway activation has been reported to be involved in mice liver fibrosis induced by hepatitis viru...

    Authors: Lan Chen, Xiaofang Ji, Manni Wang, Xiaoyan Liao, Cuiying Liang, Juanjuan Tang, Zhencheng Wen, Ferrandon Dominique and Zi Li

    Citation: Parasites & Vectors 2021 14:279

    Content type: Research

    Published on:

  23. The liver fluke Fasciola gigantica secretes excretory-secretory proteins during infection to mediate its interaction with the host. In this study, we investigated the immunomodulatory effects of a recombinant teg...

    Authors: Muhammad Ehsan, Rui-Si Hu, Jun-Ling Hou, Hany M. Elsheikha, Xiao-Dong Li, Pan-Hong Liang and Xing-Quan Zhu

    Citation: Parasites & Vectors 2021 14:276

    Content type: Research

    Published on:

  24. The blood flukes of genus Schistosoma are the causative agent of schistosomiasis, a parasitic disease that infects more than 200 million people worldwide. Proteases of schistosomes are involved in critical steps ...

    Authors: Lenka Ulrychová, Pavel Ostašov, Marta Chanová, Michael Mareš, Martin Horn and Jan Dvořák

    Citation: Parasites & Vectors 2021 14:274

    Content type: Research

    Published on:

  25. Cystic echinococcosis (CE) is a parasitic zoonosis caused by infection with the larval stage of Echinococcus granulosus (s.l.). This study investigated the prevalence and potential risk factors associated with hu...

    Authors: Leonardo Uchiumi, Guillermo Mujica, Daniel Araya, Juan Carlos Salvitti, Mariano Sobrino, Sergio Moguillansky, Alejandro Solari, Patricia Blanco, Fabiana Barrera, Janete Lamunier, Marcos Arezo, Marcos Seleiman, Zaida E. Yadon, Francesca Tamarozzi, Adriano Casulli and Edmundo Larrieu

    Citation: Parasites & Vectors 2021 14:262

    Content type: Research

    Published on:

  26. Toxocariasis, caused by a nematode species of the genus Toxocara, has been described as one of the most prevalent zoonotic helminthiases worldwide. Human transmission may occur by ingesting Toxocara spp. larvae f...

    Authors: Paula Andreia Fabris Giudice, Susana Angélica Zevallos Lescano, William Henry Roldan Gonzáles, Rogério Giuffrida, Fernanda Nobre Bandeira, Louise Bach Kmetiuk, Andrea Pires dos Santos, Alexander Welker Biondo and Vamilton Alvares Santarém

    Citation: Parasites & Vectors 2021 14:250

    Content type: Research

    Published on:

  27. Wolbachia is an obligate intracellular maternally transmitted, gram-negative bacterium which forms a spectrum of endosymbiotic relationships from parasitism to obligatory mutualism in a wide range of arthropods a...

    Authors: Ranju Ravindran Santhakumari Manoj, Maria Stefania Latrofa, Sara Epis and Domenico Otranto

    Citation: Parasites & Vectors 2021 14:245

    Content type: Review

    Published on:

  28. Genetic markers are employed widely in molecular studies, and their utility depends on the degree of sequence variation, which dictates the type of application for which they are suited. Consequently, the suit...

    Authors: Abigail Hui En Chan, Kittipong Chaisiri, Sompob Saralamba, Serge Morand and Urusa Thaenkham

    Citation: Parasites & Vectors 2021 14:233

    Content type: Research

    Published on:

  29. There are more than 300 species of capillariids that parasitize various vertebrate groups worldwide. Species identification is hindered because of the few taxonomically informative structures available, making...

    Authors: Victor Hugo Borba, Coralie Martin, José Roberto Machado-Silva, Samanta C. C. Xavier, Flávio L. de Mello and Alena Mayo Iñiguez

    Citation: Parasites & Vectors 2021 14:230

    Content type: Research

    Published on:

  30. Dirofilariosis is a vector-borne parasitosis caused by filarial nematodes of the genus Dirofilaria. In humans, who represent accidental hosts, dirofilariosis is mostly caused by Dirofilaria repens and Dirofilaria...

    Authors: Katharina Riebenbauer, Philipp B. Weber, Julia Walochnik, Franz Karlhofer, Stefan Winkler, Sonja Dorfer, Herbert Auer, Julia Valencak, Martin Laimer and Alessandra Handisurya

    Citation: Parasites & Vectors 2021 14:227

    Content type: Research

    Published on:

  31. The current studies compared ProHeart® 12, Heartgard® Plus and Interceptor® Plus for preventive efficacy against JYD-34, a macrocyclic lactone (ML)-resistant strain of Dirofilaria immitis in dogs.

    Authors: Tom L. McTier, Susan Holzmer, Kristina Kryda, Sean Mahabir, John W. McCall, Jami Trombley and Steven J. Maeder

    Citation: Parasites & Vectors 2021 14:226

    Content type: Research

    Published on:

  32. Schistosomiasis is a chronic parasitic disease that affects millions of people’s health worldwide. Because of the increasing drug resistance to praziquantel (PZQ), which is the primary drug for schistosomiasis...

    Authors: Gongming Li, Qingqing Guo, Chao Feng, Huan Chen, Wenjiao Zhao, Shu Li, Yang Hong and Dequn Sun

    Citation: Parasites & Vectors 2021 14:225

    Content type: Research

    Published on:

  33. Schsistosomiasis is endemic in sub-Saharan Africa. It is transmitted by intermediate host snails such as Bulinus and Biomphalaria. An understanding of the abundance and distribution of snail vectors is important ...

    Authors: Tawanda Manyangadze, Moses John Chimbari, Owen Rubaba, White Soko and Samson Mukaratirwa

    Citation: Parasites & Vectors 2021 14:222

    Content type: Research

    Published on:

  34. The systematic of several marine diphyllobothriid tapeworms of pinnipeds has been revised in recent years. However, 20 species of Diphyllobothrium from phocids and otariids are still recognized as incertae sedis....

    Authors: Jesús S. Hernández-Orts, Tetiana A. Kuzmina, Luis A. Gomez-Puerta and Roman Kuchta

    Citation: Parasites & Vectors 2021 14:219

    Content type: Research

    Published on:

  35. Cystic echinococcosis (CE) has a worldwide distribution and is especially prevalent in North African countries. With a mean annual surgical incidence (ASI) of CE of 12.7 per 100,000 inhabitants, Tunisia is one...

    Authors: Selim M’rad, Raja Chaâbane-Banaoues, Massaouda Ghrab, Hamouda Babba and Myriam Oudni-M’rad

    Citation: Parasites & Vectors 2021 14:216

    Content type: Research

    Published on:

  36. Cystic echinococcosis (CE) is a disease caused by the larval stage of Echinococcus granulosus sensu lato  (s.l.). The treatment of CE mainly relies on the use of benzimidazoles, which can commonly cause adverse s...

    Authors: Mohammad Reza Shiee, Eshrat Beigom Kia, Farzaneh Zahabiun, Mahmood Naderi, Elahe Motevaseli, Shahram Nekoeian, Majid Fasihi Harandi and Ahmad Reza Dehpour

    Citation: Parasites & Vectors 2021 14:197

    Content type: Research

    Published on:

  37. Current data about Pseudaliidae show contrasting patterns of host specificity between congeneric species. We investigated how both contact and compatibility between hosts and parasites contributed to the patte...

    Authors: Rachel Pool, Clara Romero-Rubira, Juan Antonio Raga, Mercedes Fernández and Francisco Javier Aznar

    Citation: Parasites & Vectors 2021 14:196

    Content type: Research

    Published on:

  38. Schistosomiasis remains a major public health concern in sub-Saharan Africa. Although schistosomiasis is well documented in school-aged children in Burkina Faso, prevalence data among preschool-aged children (...

    Authors: Mamoudou Cisse, Ibrahim Sangare, Arthur D. Djibougou, Marc C. Tahita, Souleymane Gnissi, Jonathan K. W. Bassinga, Salifou Konda and Abdoulaye H. Diallo

    Citation: Parasites & Vectors 2021 14:185

    Content type: Research

    Published on:

  39. Cystic echinococcosis (CE) affects predominantly young patients in highly endemic areas. Improved serological methods are needed for the follow-up of CE cases, especially given the high rates of post-surgical ...

    Authors: Eya Ben Salah, Coralie Barrera, Sana Mosbahi, Bruno Gottstein, Mar Siles-Lucas, Samia Belhassen, Abdellatif Nouri, Hamouda BABBA, Laurence Millon and Wahiba Sakly

    Citation: Parasites & Vectors 2021 14:180

    Content type: Research

    Published on:

  40. Ascaris lumbricoides is the most common causative agent of soil-transmitted helminth infections worldwide, with an estimated 450 million people infected with this nematode globally. It is suggested that helminths...

    Authors: Norashikin Mohd-Shaharuddin, Yvonne Ai Lian Lim, Romano Ngui and Sheila Nathan

    Citation: Parasites & Vectors 2021 14:176

    Content type: Research

    Published on:

  41. An accurate test for the diagnosis and post-treatment follow-up of patients with schistosomiasis is needed. We assessed the performance of different laboratory parameters, including the up-converting reporter ...

    Authors: Francesca Tamarozzi, Tamara Ursini, Pytsje T. Hoekstra, Ronaldo Silva, Cecilia Costa, Federico Gobbi, Gerardo B. Monteiro, Leonardo Motta, Govert J. van Dam, Paul L. Corstjens, Lisette van Lieshout and Dora Buonfrate

    Citation: Parasites & Vectors 2021 14:149

    Content type: Research

    Published on:

  42. Species of Trichinella are globally important foodborne parasites infecting a number of domestic and wild vertebrates, including humans. Free-ranging carnivores can act as sentinel species for detection of Trichi...

    Authors: Rajnish Sharma, N. Jane Harms, Piia M. Kukka, Thomas S. Jung, Sarah E. Parker, Sasha Ross, Peter Thompson, Benjamin Rosenthal, Eric P. Hoberg and Emily J. Jenkins

    Citation: Parasites & Vectors 2021 14:146

    Content type: Research

    Published on:

  43. Capillaria aerophila and Capillaria boehmi parasitize the respiratory system of wild and domestic carnivores. Capillaria aerophila inhabits the trachea and bronchi of dogs and cats, while C. boehmi affects the na...

    Authors: Angela Di Cesare, Simone Morelli, Giulia Morganti, Giulia Simonato, Fabrizia Veronesi, Mariasole Colombo, Michele Berlanda, Wilfried Lebon, Matilde Gallo, Frederic Beugnet and Donato Traversa

    Citation: Parasites & Vectors 2021 14:143

    Content type: Research

    Published on:

  44. Blood parasites have been the subject of much research, with numerous reports of the presence of microfilariae in the peripheral blood (circulating microfilariae) of birds belonging to many orders. Current lim...

    Authors: Rasa Binkienė, Carolina Romeiro Fernandes Chagas, Rasa Bernotienė and Gediminas Valkiūnas

    Citation: Parasites & Vectors 2021 14:137

    Content type: Research

    Published on:

  45. Schistosomiasis is a highly prevalent parasitic disease that can lead to adverse maternal and perinatal outcomes. To our knowledge, there has been no systematic review and meta-analysis of schistosomiasis duri...

    Authors: Ishag Adam, Nadiah A. ALhabardi, Osama Al-Wutayd and Ammar H. Khamis

    Citation: Parasites & Vectors 2021 14:133

    Content type: Review

    Published on: