Qian M-B, Utzinger J, Keiser J, Zhou X-N. Clonorchiasis. Lancet. 2016;387:800–10.
Article
Google Scholar
Deng ZH, Fang YY, Zhang QM, Mao Q, Pei FQ, Liu MR. The control of clonorchiasis in Guangdong province, southern China. Acta Trop. 2020;202:105246.
Article
Google Scholar
Na BK, Pak JH, Hong SJ. Clonorchis sinensis and clonorchiasis. Acta Trop. 2020;203:105309.
Article
CAS
Google Scholar
Wang D, Young ND, Korhonen PK, Gasser RB. Clonorchis sinensis and clonorchiasis: the relevance of exploring genetic variation. Adv Parasitol. 2018;100:155–208.
Article
Google Scholar
Nelson NP, Easterbrook PJ, McMahon BJ. Epidemiology of hepatitis B virus infection and impact of vaccination on disease. Clin Liver Dis. 2016;20:607–28.
Article
Google Scholar
Wang H, Men P, Xiao Y, Gao P, Lv M, Yuan Q, et al. Hepatitis B infection in the general population of China: a systematic review and meta-analysis. BMC Infect Dis. 2019;19:811.
Article
Google Scholar
Shi Y, Jiang Z, Yang Y, Zheng P, Wei H, Lin Y, et al. Clonorchis sinensis infection and co-infection with the hepatitis B virus are important factors associated with cholangiocarcinoma and hepatocellular carcinoma. Parasitol Res. 2017;116:2645–9.
Article
Google Scholar
Gao Y, Li Y, Liu X, Zhang T, Yu G, Wang Y, et al. High prevalence of Clonorchis sinensis infections and coinfection with hepatitis virus in riverside villages in northeast China. Sci Rep-Uk. 2020;10:11749.
Article
CAS
Google Scholar
Xie F. Clinical significance of Clonorchis sinensis antibodies dectection in HBV. Chinese J Parasitic Dis Control. 2005;2:95–8 (in Chinese).
Mou H, Wang L, Wang J, Jin B, Jin H. Discussion on clonorchiasis and HBV. Heilongjiang Med J Pharm. 2009;32:94.
Google Scholar
Meng Z, Chen Y, Lu M. Advances in targeting the innate and adaptive immune systems to cure chronic hepatitis B virus infection. Front Immunol. 2020;10:3127. https://doi.org/10.3389/fimmu.2019.03127.
Koda S, Zhu X, Zheng K, Yan C. Molecular mechanisms of Clonorchis sinensis-host interactions and implications for vaccine development. Front Cell Dev Biol. 2022;9:781768. https://doi.org/10.3389/fcell.2021.781768.
Kong D, Li X, Zhang B, Yan C, Tang R, Zheng K. The characteristics of CD4(+)T-helper cell subset differentiation in experimental Clonorchis sinensis-infected FVB mice. Iran J Basic Med Sci. 2020;23:1538–43.
Google Scholar
Li W, Dong H, Huang Y, Chen T, Kong X, Sun H, et al. Clonorchis sinensis co-infection could affect the disease state and treatment response of HBV patients. Plos Neglect Trop D. 2016;10:e4806.
Article
Google Scholar
Wang X, Chen W, Huang Y, Sun J, Men J, Liu H, et al. The draft genome of the carcinogenic human liver fluke Clonorchis sinensis. Genome Biol. 2011;12:R107.
Article
CAS
Google Scholar
Zhao L, Shi M, Zhou L, Sun H, Zhang X, He L, et al. Clonorchis sinensis adult-derived proteins elicit Th2 immune responses by regulating dendritic cells via mannose receptor. PLoS Negl Trop Dis. 2018;12:e6251.
Article
Google Scholar
Chai J. Praziquantel treatment in trematode and cestode infections: an update. Infect Chemother. 2013;45:32–43.
Article
CAS
Google Scholar
Hines-Kay J. Transcriptional analysis of Schistosoma mansoni treated with sub-lethal doses of the anthelmintic drug praziquantel. MSc thesis. Albuquerque: University of New Mexico; 2011.
Xiao Y, Liu C, Tang W, Zhang H, Chen X. Evans blue inhibits HBV replication through a dual antiviral mechanism by targeting virus binding and capsid assembly. Front Microbiol. 2019;10:2638. https://doi.org/10.3389/fmicb.2019.02638.
Adnani Sadati SJ, Farahnak A, Molaei Rad MB, Golestani A, Eshraghiyan MR. A comparison between the effects of albendazole and mebendazole on the enzymatic activity of excretory/secretory products of Echinococcus granulosus protoscoleces in vitro. Iran J Public Health. 2016;45:223–9.
Google Scholar
Li Z, Cao H, Yao M, Lei X. Effect of acupuncture combined with Shenqi Yigan Decoction on liver function and T cell subsets in patients with HBV-induced liver fibrosis. Am J Transl Res. 2021;13:3409–17.
CAS
Google Scholar
Königshofer P, Hofer BS, Brusilovskaya K, Simbrunner B, Petrenko O, Wöran K, et al. Distinct structural and dynamic components of portal hypertension in different animal models and human liver disease etiologies. Hepatology. 2022;75:610–22.
Article
Google Scholar
Enomoto H, Bando Y, Nakamura H, Nishiguchi S, Koga M. Liver fibrosis markers of nonalcoholic steatohepatitis. World J Gastroentero. 2015;21:7427–35.
Article
CAS
Google Scholar
Matsumoto T, Aoki T, Shimizu T, Park KH, Shiraki T, Sakuraoka Y, et al. Prognostic significance of preoperative hyaluronic acid level in patients with hepatocellular carcinoma. HPB (Oxford). 2022;24:525–34.
Article
Google Scholar
Wong VS, Hughes V, Trull A, Wight DGD, Petrik J, Alexander GJM. Serum hyaluronic acid is a useful marker of liver fibrosis in chronic hepatitis C virus infection. J Viral Hepatitis. 1998;5:187–92.
Article
CAS
Google Scholar
Gudowska M, Gruszewska E, Panasiuk A, Cylwik B, Flisiak R, Świderska M, et al. Hyaluronic acid concentration in liver diseases. Clin Exp Med. 2016;16:523–8.
Article
CAS
Google Scholar
Tran A, Hastier P, Barjoan EM, Demuth N, Pradier C, Saint-Paul MC, et al. Non invasive prediction of severe fibrosis in patients with alcoholic liver disease. Gastroenterol Clin Biol. 2000;24:626–30.
CAS
Google Scholar
Jin H, Li Z. Correlation between serum hyaluronic acid and HBV DNA levels in patients with hepatitis B-associated cirrhosis. Shijie Huaren Xiaohua Zazhi. 2012;20:229–32.
CAS
Google Scholar
Li D, He L, Guo H, Chen H, Shan H. Targeting activated hepatic stellate cells (aHSCs) for liver fibrosis imaging. Ejnmmi Res. 2015;5:71.
Article
Google Scholar
Sherman MH. Stellate cells in tissue repair, inflammation, and cancer. Annu Rev Cell Dev Biol. 2018;34:333–55.
Article
CAS
Google Scholar
Puche JE, Saiman Y, Friedman SL. Hepatic stellate cells and liver fibrosis. Compr Physiol. 2013;3:1473–92.
Article
Google Scholar
Mallat A, Lotersztajn S. Cellular mechanisms of tissue fibrosis 5 novel insights into liver fibrosis. Am J Physiol Cell Physiol. 2013;305:789–99.
Article
Google Scholar
Parola M, Pinzani M. Liver fibrosis: Pathophysiology, pathogenetic targets and clinical issues. Mol Aspects Med. 2019;65:37–55.
Article
CAS
Google Scholar
Friedman SL. Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiol Rev. 2008;88:125–72.
Article
CAS
Google Scholar
Yang YM, Seki E. TNFα in liver fibrosis. Curr Pathobiol Rep. 2015;3:253–61.
Article
Google Scholar
Robert S, Gicquel T, Bodin A, Lagente V, Boichot E. Characterization of the MMP/TIMP imbalance and collagen production induced by IL-1β or TNF-α release from human hepatic stellate cells. PLoS ONE. 2016;11:e153118.
Article
Google Scholar
Xu L, Hui AY, Albanis E, Arthur MJ, O’Byrne SM, Blaner WS, et al. Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis. Gut. 2005;54:142–51.
Article
CAS
Google Scholar
Sun S, Li H, Yuan Y, Wang L, He W, Xie H, et al. Preventive and therapeutic effects of Trichinella spiralis adult extracts on allergic inflammation in an experimental asthma mouse model. Parasit Vectors. 2019;12:326.
Article
CAS
Google Scholar
Wangala B, Gantin RG, Voßberg PS, Vovor A, Poutouli WP, Komlan K, et al. Inflammatory and regulatory CCL and CXCL chemokine and cytokine cellular responses in patients with patent mansonella perstans filariasis. Clin Exp Immunol. 2019;196:111–22.
Article
CAS
Google Scholar
McDonald EA, Kurtis JD, Acosta L, Gundogan F, Sharma S, Pond-Tor S, et al. Schistosome egg antigens elicit a proinflammatory response by trophoblast cells of the human placenta. Infect Immun. 2013;81:704–12.
Article
CAS
Google Scholar
Guo G, Tan D, Zhu P, Liu F. Hepatitis B virus X protein promotes proliferation and upregulates TGF-beta1 and CTGF in human hepatic stellate cell line, LX-2. Hepatobil Pancreat Dis Int. 2009;8:59–64.
CAS
Google Scholar
Liu X, Zhu S, You H, Cong M, Liu T, Wang B, et al. Hepatitis B virus infects hepatic stellate cells and affects their proliferation and expression of collagen type I. Chinese Med J-Peking. 2009;122:1455–61.
CAS
Google Scholar
Wang X, Hu F, Hu X, Chen W, Huang Y, Yu X. Proteomic identification of potential Clonorchis sinensis excretory/secretory products capable of binding and activating human hepatic stellate cells. Parasitol Res. 2014;113:3063–71.
Article
Google Scholar
Shang M, Sun H, Wu Y, Gong Y, Tang Z, Meng F, et al. In vivo and in vitro studies using Clonorchis sinensis adult-derived total protein (CsTP) on cellular function and inflammatory effect in mouse and cell model. Parasitol Res. 2020;119:1641–52.
Article
Google Scholar
Jiang D, Jiang Z, Han F, Zhang Y, Li Z. HGF suppresses the production of collagen type III and α-SMA induced by TGF-β1 in healing fibroblasts. Eur J Appl Physiol. 2008;103:489–93.
Article
CAS
Google Scholar
Pinzani M, Marra F. Cytokine receptors and signaling in hepatic stellate cells. Semin Liver Dis. 2001;21:397-416. https://doi.org/10.1055/s-2001-17554.
Chen Y, Zeng Z, Shen X, Wu Z, Dong Y, Cheng JC. MicroRNA-146a-5p negatively regulates pro-inflammatory cytokine secretion and cell activation in lipopolysaccharide stimulated human hepatic stellate cells through inhibition of toll-like receptor 4 signaling pathways. Int J Mol Sci. 2016;17:1076. https://doi.org/10.3390/ijms17071076.
Hu N, Wang C, Dai X, Zhou M, Gong L, Yu L, et al. Phillygenin inhibits LPS-induced activation and inflammation of LX2 cells by TLR4/MyD88/NF-κB signaling pathway. J Ethnopharmacol. 2020;248:112361.
Article
CAS
Google Scholar
Kishimoto T. IL-6: from its discovery to clinical applications. Int Immunol. 2010;22:347–52.
Article
CAS
Google Scholar
Nieto N. Oxidative-stress and IL-6 mediate the fibrogenic effects of rodent kupffer cells on stellate cells. Hepatology. 2006;44:1487–501.
Article
CAS
Google Scholar
Xiang D, Sun W, Ning B, Zhou T, Li X, Zhong W, et al. The HLF/IL-6/STAT3 feedforward circuit drives hepatic stellate cell activation to promote liver fibrosis. Gut. 2018;67:1704.
Article
CAS
Google Scholar
Li W, Dong H, Huang Y, Chen T, Kong X, Sun H, et al. Clonorchis sinensis co-infection could affect the disease state and treatment response of HBV patients. PLoS Negl Trop Dis. 2016;10:e4806.
Article
Google Scholar
Hu X, Jiang J, Ni C, Xu Q, Ye S, Wu J, et al. HBV integration-mediated cell apoptosis in HepG2 2 15. J Cancer. 2019;10:4142–50.
Article
CAS
Google Scholar
Chang T, Gish RG, de Man R, Gadano A, Sollano J, Chao Y, et al. A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B. New Engl J Med. 2006;354:1001–10.
Article
CAS
Google Scholar
Lapinski TW, Pazgan-Simon M, Plesniak R, Sobala-Szczygiel B. Loss of HBsAg in patients with high levels of HBV DNA during treatment with nucleoside or nucleotide analogs. Hepatitis Monthly. 2020;20(10). https://doi.org/10.5812/hepatmon.106951.
Chen P, Xie Q, Lu X, Yu C, Xu K, Ruan B, et al. Serum HBeAg and HBV DNA levels are not always proportional and only high levels of HBeAg most likely correlate with high levels of HBV DNA: a community-based study. Medicine (Baltimore). 2017;96:e7766. https://doi.org/10.1097/MD.0000000000007766.
Du D, Jia Z, Li G, Zhou Y. HBV DNA vaccine with adjuvant cytokines induced specific immune responses against HBV infection. World J Gastroenterol. 2003;9:108.
Article
CAS
Google Scholar
Wang A, Guan S, Yang K, Zhang H, Sun B, Pan Y, et al. Study of IFN-inducible double-stranded RNA dependent protein kinase on antiviral activity of HBV in vitro. Chinese Pharmacol Bull. 2015;12:1254–8.
Google Scholar
Rim H, Lyu K, Lee J, Joo K. Clinical evaluation of the therapeutic efficacy of praziquantel (Embay 8440) against Clonorchis sinensis infection in man. Ann Trop Med Parasitol. 1981;75:27–33.
Article
CAS
Google Scholar
Veerakumari L, Munuswamy N. In vitro effect of some anthelmintics on lactate dehydrogenase activity of cotylophoron cotylophorum (Digenea: paramphistomidae). Vet Parasitol. 2000;91:129–40.
Article
CAS
Google Scholar
Zu-yun C, Jia-lin D, Jiang H. Effect of praziquantel, albendazole and mebendazole on recombinant lactate dehydrogenase of Taenia asiatica. Chinese J Public Health. 2010;26:553–4.
Google Scholar
Park S, Friedrich L, Yahya NA, Rohr CM, Chulkov EG, Maillard D, et al. Mechanism of praziquantel action at a parasitic flatworm ion channel. Sci Transl Med. 2021;13:j5832.
Article
Google Scholar